Literature DB >> 18998068

Role of bile acid secretion in human colorectal cancer.

Meinrad Peterlik1.   

Abstract

Cholic, deoxycholic and lithocholic acid promote tumor formation in the large intestine by a direct proliferative effect on rather undifferentiated mucosal epithelial cells. In addition, bile acids may play a role in colorectal cancer pathogenesis because they reduce the chemopreventive efficiency of calcium and vitamin D by interfering with calcium and vitamin D receptor-activated anti-mitogenic intracellular signalling in neoplastic colonocytes.

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Year:  2008        PMID： 18998068     DOI： 10.1007/s10354-008-0601-4

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN： 0043-5341


  21 in total

1.  Antiproliferative effect of 1,25-dihydroxyvitamin D3 and its analogs on human colon adenocarcinoma cells (CaCo-2): influence of extracellular calcium.

Authors:  H S Cross; C Huber; M Peterlik
Journal:  Biochem Biophys Res Commun       Date:  1991-08-30       Impact factor: 3.575

Review 2.  Can colon cancer incidence and death rates be reduced with calcium and vitamin D?

Authors:  C F Garland; F C Garland; E D Gorham
Journal:  Am J Clin Nutr       Date:  1991-07       Impact factor: 7.045

Review 3.  Vitamin D and calcium deficits predispose for multiple chronic diseases.

Authors:  M Peterlik; H S Cross
Journal:  Eur J Clin Invest       Date:  2005-05       Impact factor: 4.686

4.  Assessment of vitamin D and calcium status in healthy adult Austrians.

Authors:  S Kudlacek; B Schneider; M Peterlik; G Leb; K Klaushofer; K Weber; W Woloszczuk; R Willvonseder
Journal:  Eur J Clin Invest       Date:  2003-04       Impact factor: 4.686

5.  Tumor-enhancing effects of cholic acid are exerted on the early stages of colon carcinogenesis via induction of aberrant crypt foci with an enhanced growth phenotype.

Authors:  P K Baijal; E P Clow; D W Fitzpatrick; R P Bird
Journal:  Can J Physiol Pharmacol       Date:  1998-12       Impact factor: 2.273

6.  Vitamin D receptor as an intestinal bile acid sensor.

Authors:  Makoto Makishima; Timothy T Lu; Wen Xie; G Kerr Whitfield; Hideharu Domoto; Ronald M Evans; Mark R Haussler; David J Mangelsdorf
Journal:  Science       Date:  2002-05-17       Impact factor: 47.728

7.  Calcium ameliorates the toxic effect of deoxycholic acid on colonic epithelium.

Authors:  M J Wargovich; V W Eng; H L Newmark; W R Bruce
Journal:  Carcinogenesis       Date:  1983-09       Impact factor: 4.944

8.  Lithocholic acid can carry out in vivo functions of vitamin D.

Authors:  Jamie A Nehring; Claudia Zierold; Hector F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-29       Impact factor: 11.205

9.  Cancer prevalence in Central Europe: the EUROPREVAL Study.

Authors:  J M Lutz; S Francisci; E Mugno; M Usel; V Pompe-Kirn; J-W Coebergh; M Bieslka-Lasota
Journal:  Ann Oncol       Date:  2003-02       Impact factor: 32.976

10.  Nutritional calcium modulates colonic expression of vitamin D receptor and pregnane X receptor target genes.

Authors:  Thomas Nittke; Stephan Selig; Enikö Kallay; Heide S Cross
Journal:  Mol Nutr Food Res       Date:  2008-06       Impact factor: 5.914
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  7 in total

1.  Access to New Cytotoxic Triterpene and Steroidal Acid-TEMPO Conjugates by Ugi Multicomponent-Reactions.

Authors:  Haider N Sultani; Ibrahim Morgan; Hidayat Hussain; Andreas H Roos; Haleh H Haeri; Goran N Kaluđerović; Dariush Hinderberger; Bernhard Westermann
Journal:  Int J Mol Sci       Date:  2021-07-01       Impact factor: 5.923

2.  Colorectal cancer drug target prediction using ontology-based inference and network analysis.

Authors:  Cui Tao; Jingchun Sun; W Jim Zheng; Junjie Chen; Hua Xu
Journal:  Database (Oxford)       Date:  2015-03-27       Impact factor: 3.451

3.  Cholesterol-lowering activity of the major polyphenols in grape seed.

Authors:  Sathaporn Ngamukote; Kittana Mäkynen; Thavaree Thilawech; Sirichai Adisakwattana
Journal:  Molecules       Date:  2011-06-17       Impact factor: 4.411

4.  Dietary and the Risk of Sporadic Colorectal Cancer in China: A Case-control Study.

Authors:  Wenfei Wang; Zhaogang Dong; Xin Zhang; Wei Li; Peilong Li; Xiaoyang Chen
Journal:  Iran J Public Health       Date:  2018-09       Impact factor: 1.429

Review 5.  Vitamin D and Cancer: An Historical Overview of the Epidemiology and Mechanisms.

Authors:  Alberto Muñoz; William B Grant
Journal:  Nutrients       Date:  2022-03-30       Impact factor: 5.717

Review 6.  Role of calcium, vitamin D, and the extrarenal vitamin D hydroxylases in carcinogenesis.

Authors:  Julia Höbaus; Ursula Thiem; Doris M Hummel; Enikö Kallay
Journal:  Anticancer Agents Med Chem       Date:  2013-01       Impact factor: 2.505

7.  Relative Expression of Vitamin D Hydroxylases, CYP27B1 and CYP24A1, and of Cyclooxygenase-2 and Heterogeneity of Human Colorectal Cancer in Relation to Age, Gender, Tumor Location, and Malignancy: Results from Factor and Cluster Analysis.

Authors:  Wolfgang Brozek; Teresa Manhardt; Enikö Kállay; Meinrad Peterlik; Heide S Cross
Journal:  Cancers (Basel)       Date:  2012-07-26       Impact factor: 6.639
  7 in total

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