Expression of HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein in multiple schwannomas of the conus medullaris.

Schwannomatosis is a clinical syndrome that requires thorough clinical and radiological assessments before the diagnosis is made. Although schwannomatosis has been reported before, all were in multiple organ sites. The authors report a case of multiple intra-dural schwannomas of the conus medullaris expressing HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein; which to the best of our knowledge has not been previously reported in schwanomatosis.