BACKGROUND: Before the 1980s, Escherichia coli was the most common cause of pyogenic liver abscess, but more recently, Klebsiella pneumoniae has emerged as the most common organism in the United States and Taiwan. OBJECTIVE: Our goal is to present a case of K. pneumoniae liver abscess (KLA) and review the risk factors, presenting symptoms, complications, and treatment of this disease that is emerging in North America. CASE REPORT: We present a patient who was found to have KLA complicated by bacteremia and sepsis. CONCLUSIONS: Initially described in the Asian literature, KLA is an emerging problem in North America. We present this case to increase awareness among emergency physicians of the diagnosis, risk factors, potential complications-including bacteremia and disseminated infection-and treatment. Copyright Â
BACKGROUND: Before the 1980s, Escherichia coli was the most common cause of pyogenic liver abscess, but more recently, Klebsiella pneumoniae has emerged as the most common organism in the United States and Taiwan. OBJECTIVE: Our goal is to present a case of K. pneumoniae liver abscess (KLA) and review the risk factors, presenting symptoms, complications, and treatment of this disease that is emerging in North America. CASE REPORT: We present a patient who was found to have KLA complicated by bacteremia and sepsis. CONCLUSIONS: Initially described in the Asian literature, KLA is an emerging problem in North America. We present this case to increase awareness among emergency physicians of the diagnosis, risk factors, potential complications-including bacteremia and disseminated infection-and treatment. Copyright Â
Authors: Andreas M Lenz; Mark Fairweather; James C Peyton; Sarah A Gardner; William G Cheadle Journal: Inflamm Res Date: 2010-10-26 Impact factor: 4.575
Authors: Debanu Das; Piotr Kozbial; Gye Won Han; Dennis Carlton; Lukasz Jaroszewski; Polat Abdubek; Tamara Astakhova; Herbert L Axelrod; Constantina Bakolitsa; Connie Chen; Hsiu Ju Chiu; Michelle Chiu; Thomas Clayton; Marc C Deller; Lian Duan; Kyle Ellrott; Marc André Elsliger; Dustin Ernst; Carol L Farr; Julie Feuerhelm; Anna Grzechnik; Joanna C Grant; Kevin K Jin; Hope A Johnson; Heath E Klock; Mark W Knuth; S Sri Krishna; Abhinav Kumar; David Marciano; Daniel McMullan; Mitchell D Miller; Andrew T Morse; Edward Nigoghossian; Amanda Nopakun; Linda Okach; Silvya Oommachen; Jessica Paulsen; Christina Puckett; Ron Reyes; Christopher L Rife; Natasha Sefcovic; Henry J Tien; Christine B Trame; Henry van den Bedem; Dana Weekes; Tiffany Wooten; Qingping Xu; Keith O Hodgson; John Wooley; Ashley M Deacon; Adam Godzik; Scott A Lesley; Ian A Wilson Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2009-10-27