Literature DB >> 18992622

Systemic therapy for metastatic renal cell carcinoma.

Glenn S Kroog1, Robert J Motzer.   

Abstract

Renal cell cancer (RCC) is the most common form of cancer of the kidney and accounts for approximately 44,000 cases per year in the United States. Historically, only immunotherapy showed activity in metastatic RCC. The improved survival and quality of life for patients with metastatic RCC over the last several years are direct results of advances made in understanding the development of RCC. Three targeted therapies-sunitinib, sorafenib, and temsirolimus-have been approved for use in the United States recently. Current research is aimed at developing new drugs and combining available drugs to improve upon the responses and survival seen with approved single agents.

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Year:  2008        PMID: 18992622     DOI: 10.1016/j.ucl.2008.07.007

Source DB:  PubMed          Journal:  Urol Clin North Am        ISSN: 0094-0143            Impact factor:   2.241


  10 in total

Review 1.  Multi-modal treatment for metastatic renal cancer: the role of surgery.

Authors:  Paul Russo
Journal:  World J Urol       Date:  2010-04-04       Impact factor: 4.226

Review 2.  Adjuvant and neoadjuvant therapy in renal cell carcinoma.

Authors:  Michel Choueiri; Nizar Tannir; Eric Jonasch
Journal:  Curr Clin Pharmacol       Date:  2011-08

Review 3.  Emerging critical role of molecular testing in diagnostic genitourinary pathology.

Authors:  George J Netto; Liang Cheng
Journal:  Arch Pathol Lab Med       Date:  2012-04       Impact factor: 5.534

4.  Perfusion CT in solid body-tumours. Part II: Clinical applications and future development.

Authors:  M Bellomi; S Viotti; L Preda; G D'Andrea; L Bonello; G Petralia
Journal:  Radiol Med       Date:  2010-03-09       Impact factor: 3.469

5.  Underactivation of the adiponectin-adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression.

Authors:  Nir Kleinmann; Wilhelmina C M Duivenvoorden; Sarah N Hopmans; Laura K Beatty; Shengjun Qiao; Daniel Gallino; Sarka Lhotak; Dean Daya; Athanasios Paschos; Richard C Austin; Jehonathan H Pinthus
Journal:  Clin Exp Metastasis       Date:  2013-10-05       Impact factor: 5.150

6.  Upper gastrointestinal bleeding revealing the stomach metastases of renal cell carcinoma.

Authors:  Rizwan Kibria; Kanan Sharma; Syed A Ali; Pallavi Rao
Journal:  J Gastrointest Cancer       Date:  2009-06-10

7.  Everolimus: in advanced renal cell carcinoma.

Authors:  Karly P Garnock-Jones; Gillian M Keating
Journal:  Drugs       Date:  2009-10-22       Impact factor: 9.546

Review 8.  Synergistic combinations of signaling pathway inhibitors: mechanisms for improved cancer therapy.

Authors:  Paul Dent; David T Curiel; Paul B Fisher; Steven Grant
Journal:  Drug Resist Updat       Date:  2009-04-22       Impact factor: 18.500

9.  Fatigue in renal cell carcinoma: the hidden burden of current targeted therapies.

Authors:  James M G Larkin; Lynda M Pyle; Martin E Gore
Journal:  Oncologist       Date:  2010-11-04

Review 10.  Nephrotoxicity of recent anti-cancer agents.

Authors:  Norbert Lameire
Journal:  Clin Kidney J       Date:  2013-11-26
  10 in total

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