| Literature DB >> 18992309 |
Julien Renvoise1, Delphine Burlot, Gérard Marin, Christophe Derail.
Abstract
This work deals with the rheological behavior and adherence properties of pressure sensitive adhesive formulations dedicated to medical applications. We have developed a specific viscoelastic substrate which mimics adhesion on human skin to measure the adherence properties of PSAs when they are stuck on the human skin. By comparing peeling results of PSAs, dedicated to medical applications, stuck on human skin and on this viscoelastic substrate we show that this substrate, based on a blend of natural proteins, presents a better representation of the interactions occurring at the skin/adhesive interface than conventional substrates used for peel test (i.e. glass and steel).Entities:
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Year: 2008 PMID: 18992309 DOI: 10.1016/j.ijpharm.2008.09.056
Source DB: PubMed Journal: Int J Pharm ISSN: 0378-5173 Impact factor: 5.875