| Literature DB >> 18991209 |
Dinesh Kumar Agrawal1, Dharmendra Saikia, Richa Tiwari, Shweta Ojha, Karuna Shanker, Jonnala Kotesh Kumar, Anil Kumar Gupta, Sudeep Tandon, Arvind Singh Negi, Suman Preet Khanuja.
Abstract
Demethoxycurcumin, isolated from the rhizomes of Curcuma longa, was found to possess antitubercular activity against Mycobacterium tuberculosis H (37)Rv strain at 200 microg/mL. Derivatisation of this active principle yielded a potent agent 6, exhibiting considerable activity with a minimum inhibitory concentration (MIC) value of 7.8 microg/mL. H (37)Rv:Mycobacterium tuberculosis H (37)Rv strain MIC:minimum inhibitory concentration.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18991209 DOI： 10.1055/s-0028-1088335
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352