Literature DB >> 189900

Effect of methylazoxymethanol acetate on adenylate cyclase and 5'-nucleotidase in rat liver plasma membranes.

M S Zedeck, N I Swislocki.   

Abstract

A single tumorigenic dose of methylazoxymethanol acetate increased adenylate cyclase activity in total liver homogenates 70-100% by the seventh day after treatment. The increased activity occurred in the plasma membranes rather than in the nuclei and was accompanied by a significant increase in 5'-nucleotidase activity. The data indicate that the carcinogen may alter the structure of the plasma membrane.

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Year:  1975        PMID: 189900     DOI: 10.1016/s0304-3835(75)95764-x

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  2 in total

1.  Disruption of layers 3 and 4 during development results in altered thalamocortical projections in ferret somatosensory cortex.

Authors:  S C Noctor; S L Palmer; D F McLaughlin; S L Juliano
Journal:  J Neurosci       Date:  2001-05-01       Impact factor: 6.167

2.  Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury.

Authors:  Sandeep Khurana; Nirish Shah; Kunrong Cheng; Brian Shiu; Roxana Samimi; Angelica Belo; Jasleen Shant; Cinthia Drachenberg; Jürgen Wess; Jean-Pierre Raufman
Journal:  J Pharmacol Exp Ther       Date:  2010-03-02       Impact factor: 4.030

  2 in total

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