| Literature DB >> 189900 |
Abstract
A single tumorigenic dose of methylazoxymethanol acetate increased adenylate cyclase activity in total liver homogenates 70-100% by the seventh day after treatment. The increased activity occurred in the plasma membranes rather than in the nuclei and was accompanied by a significant increase in 5'-nucleotidase activity. The data indicate that the carcinogen may alter the structure of the plasma membrane.Entities:
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Year: 1975 PMID: 189900 DOI: 10.1016/s0304-3835(75)95764-x
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679