Literature DB >> 18987531

Interobserver reproducibility in the interpretation of 99mTc-labelled white blood cell scintigraphic images.

Marianne C Tondeur1, Alain Sand, Hamphrey H Ham.   

Abstract

OBJECTIVE: This study was performed to investigate the interobserver reproducibility of the interpretation of Tc-labelled white blood cell scans combined or not with other nuclear medicine procedures.
METHODS: Twenty nuclear medicine physicians working in Belgium received clinical data and scintigraphic images from 10 patients suspected of suffering from various infectious diseases. They had to choose, for each patient, one answer among 'high probability', 'intermediate probability' and 'low probability' of infection. In a first step the level of agreement, defined as the highest percentage obtained among the three proposed answers, was calculated for each case; complete agreement was arbitrarily defined when 80% or more of the observers gave the same answer. In a second step, a numerical score was given for each answer and for each observer. The scores were defined as 0 for the 'low probability' answer, 1 for the 'intermediate probability' and 2 for the 'high probability' answer. The scores of each observer were summed up allowing obtaining of a cumulated score for each observer; observers were thereafter classified as a function of their own cumulated score.
RESULTS: An agreement of 80% or more was observed only in three patients. The cumulated scores of the observers were between 4 and 16, demonstrating that some observers were more sensitive than others.
CONCLUSION: Interobserver reproducibility in the interpretation of the white blood cell scan was poor; several factors could explain these results, the most frequent being both the poor specificity of the labelled white blood cell scan and different concepts in interpreting combined nuclear medicine procedures in several situations. As observers received the anonymized overall results, this study may have a favourable impact on continuing education in medical imaging.

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Year:  2008        PMID: 18987531     DOI: 10.1097/MNM.0b013e328310897c

Source DB:  PubMed          Journal:  Nucl Med Commun        ISSN: 0143-3636            Impact factor:   1.690


  3 in total

1.  Image acquisition and interpretation criteria for 99mTc-HMPAO-labelled white blood cell scintigraphy: results of a multicentre study.

Authors:  Paola A Erba; Andor W J M Glaudemans; Niels C Veltman; Martina Sollini; Marta Pacilio; Filippo Galli; Rudi A J O Dierckx; Alberto Signore
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-11-26       Impact factor: 9.236

2.  A large retrospective single-centre study to define the best image acquisition protocols and interpretation criteria for white blood cell scintigraphy with ⁹⁹mTc-HMPAO-labelled leucocytes in musculoskeletal infections.

Authors:  Andor W J M Glaudemans; Erik F J de Vries; Liliane E M Vermeulen; Riemer H J A Slart; Rudi A J O Dierckx; Alberto Signore
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-07-17       Impact factor: 9.236

3.  Clinical utility of indium 111-labeled white blood cell scintigraphy for evaluation of suspected infection.

Authors:  Sarah S Lewis; Gary M Cox; Jason E Stout
Journal:  Open Forum Infect Dis       Date:  2014-09-17       Impact factor: 3.835

  3 in total

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