| Literature DB >> 18986204 |
Douglass F Taber1, James F Berry, Timothy J Martin.
Abstract
A strategy for the facile alpha-amination of carboxylic acid menthyl esters is described. The resulting diastereomers, readily separable, can be individually carried on to each enantiomer of the FMOC alpha-amino acid. A variety of unnatural side chains were compatible with this approach. The menthyl ester was easily removed from the FMOC alpha-amino acid without racemization.Entities:
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Year: 2008 PMID： 18986204 DOI： 10.1021/jo801781v
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354