Literature DB >> 18985564

[Immunotherapy for cancer--modern immunologic strategies in oncology].

N Halama1, I Zoernig, D Jäger.   

Abstract

Immunotherapies have become an integral part of modern treatment concepts in oncology. The complexity of the regulation of the immune system gives rise to a multitude of different treatment approaches. Antibody based strategies are already used routinely in clinical day to day practice. Identification of new target antigens and the analysis of broader immunologic implications of antibody therapy are recent developments in this field. Antigen selection is also of high importance in the field of vaccination strategies. Vaccination strategies are now being investigated in adjuvant treatment settings but also the combination of vaccination and other treatment modalities show promising results in clinical trials. Another promising emerging field are T cell based therapies, with the clinically successful adoptive T cell transfer now being complemented by T cell receptor transfer strategies. This review summarizes the current concepts and future perspectives in immunotherapies for cancer.

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Year:  2008        PMID: 18985564     DOI: 10.1055/s-0028-1091251

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  2 in total

1.  Training the Defense System for Modern-Day Warfare: The Horizons for Immunotherapy and Vaccines for Cancer.

Authors:  Narendra Kumar; Jayshree Mishra; Sohel H Quazi
Journal:  J immunodefic Disord       Date:  2012-07-21

Review 2.  Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis.

Authors:  Jayshree Mishra; Joseph Drummond; Sohel H Quazi; Satya Sridhar Karanki; J J Shaw; Ben Chen; Narendra Kumar
Journal:  Crit Rev Oncol Hematol       Date:  2012-10-23       Impact factor: 6.312

  2 in total

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