Tien Y Wong1, Leslie Hyman. 1. Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia. twong@unimelb.edu.au
Abstract
PURPOSE: To review major findings of population-based studies in ophthalmology, to summarize key questions, and to highlight future directions for this study design. DESIGN: Summary and critical analysis of major population-based studies in eye diseases. METHODS: Literature review and interpretation. RESULTS: In the last 30 years, there have been many population-based studies in ophthalmology conducted in the United States and other countries around the world. These studies have provided information on the epidemiology of visual loss and the major eye diseases associated with visual loss; the risk factors; and the socioeconomic burden of eye disease. Population-based studies remain the most valid to determine the prevalence and incidence of a disease, and the population-attributable risk of new risk factors, including the interaction of genetic markers with systemic and environmental factors. Repeated surveys over time may also demonstrate impact of preventive strategies. CONCLUSIONS: Population-based studies have provided substantial data on the frequency and impact of the major eye diseases in the community. This study design will continue to have an important role in addressing key questions of why eye diseases occur, who is at highest risk, and what preventive and therapeutic strategies are necessary to eliminate these diseases.
PURPOSE: To review major findings of population-based studies in ophthalmology, to summarize key questions, and to highlight future directions for this study design. DESIGN: Summary and critical analysis of major population-based studies in eye diseases. METHODS: Literature review and interpretation. RESULTS: In the last 30 years, there have been many population-based studies in ophthalmology conducted in the United States and other countries around the world. These studies have provided information on the epidemiology of visual loss and the major eye diseases associated with visual loss; the risk factors; and the socioeconomic burden of eye disease. Population-based studies remain the most valid to determine the prevalence and incidence of a disease, and the population-attributable risk of new risk factors, including the interaction of genetic markers with systemic and environmental factors. Repeated surveys over time may also demonstrate impact of preventive strategies. CONCLUSIONS: Population-based studies have provided substantial data on the frequency and impact of the major eye diseases in the community. This study design will continue to have an important role in addressing key questions of why eye diseases occur, who is at highest risk, and what preventive and therapeutic strategies are necessary to eliminate these diseases.
Authors: Rafael S Grajewski; Beatrice Schuler-Thurner; Cornelia Mauch; Nicole Kreuzberg; Konrad R Koch; Antonio Bergua; Claus Cursiefen; Ludwig M Heindl Journal: Graefes Arch Clin Exp Ophthalmol Date: 2014-01-22 Impact factor: 3.117
Authors: Sophie Rogers; Rachel L McIntosh; Ning Cheung; Lyndell Lim; Jie Jin Wang; Paul Mitchell; Jonathan W Kowalski; Hiep Nguyen; Tien Y Wong Journal: Ophthalmology Date: 2010-02 Impact factor: 12.079
Authors: Eva K Fenwick; Peng Guan Ong; Charumathi Sabanayagam; Gwyn Rees; Jing Xie; Edith Holloway; Ching-Yu Cheng; Tien Y Wong; Blanche Lim; Pok Chien Tan; Ecosse L Lamoureux Journal: Qual Life Res Date: 2015-09-29 Impact factor: 4.147
Authors: Eva K Fenwick; Ryan E K Man; Chui Ming Gemmy Cheung; Charumathi Sabanayagam; Ching-Yu Cheng; Kumari Neelam; Jacqueline Chua; Alfred T L Gan; Paul Mitchell; Tien Y Wong; Ecosse L Lamoureux Journal: JAMA Ophthalmol Date: 2017-05-01 Impact factor: 7.389
Authors: Usha Chakravarthy; Tien Y Wong; Astrid Fletcher; Elisabeth Piault; Christopher Evans; Gergana Zlateva; Ronald Buggage; Andreas Pleil; Paul Mitchell Journal: BMC Ophthalmol Date: 2010-12-13 Impact factor: 2.209