Literature DB >> 18983901

A new cytotoxic guaianolide from Chrysanthemum boreale.

Ki Hun Park1, Min Suk Yang, Moon Ki Park, Sang Chan Kim, Chae Ha Yang, Sook Jahr Park, Jong Rok Lee.   

Abstract

A new cytotoxic guaianolide was isolated from Chrysanthemum boreale Makino. The structure of guaianolide was elucidated as 8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide (1). Compound 1 exhibited cytotoxic activity (IC(50)< or =4 microg/ml) against all five human cancer cell lines tested.

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Year:  2008        PMID： 18983901     DOI： 10.1016/j.fitote.2008.09.013

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  1 in total

1.  β-Caryophyllene in the Essential Oil from Chrysanthemum Boreale Induces G1 Phase Cell Cycle Arrest in Human Lung Cancer Cells.

Authors:  Kyung-Sook Chung; Joo Young Hong; Jeong-Hun Lee; Hae-Jun Lee; Ji Yeon Park; Jung-Hye Choi; Hee-Juhn Park; Jongki Hong; Kyung-Tae Lee
Journal:  Molecules       Date:  2019-10-18       Impact factor: 4.411
  1 in total

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