Kristina Y Lem1, Geoffrey T Fosgate, Bo Norby, Jörg M Steiner. 1. Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Abstract
OBJECTIVE: To estimate associations between dietary factors and pancreatitis in dogs. Design-Retrospective case-control study. ANIMALS: 198 dogs with a clinical diagnosis of pancreatitis and 187 control dogs with a diagnosis of renal failure without clinical evidence of pancreatitis. PROCEDURES: Information on signalment, weight, body condition, dietary intake, medical history, diagnostic tests performed, concurrent diseases, treatments, duration of hospitalization, and discharge status was extracted from medical records. Information on dietary intake, signalment, weight, and medical, surgical, and environmental history was collected through a telephone questionnaire. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals. RESULTS: On the basis of information extracted from the medical record, ingesting unusual food items (OR, 4.3) increased the odds of pancreatitis. On the basis of information gathered through the telephone questionnaire, ingesting unusual food items (OR, 6.1), ingesting table scraps the week before diagnosis (OR, 2.2) or throughout life (OR, 2.2), and getting into the trash (OR, 13.2) increased the odds of pancreatitis. Multivariable modeling indicated that reporting exposure to > or = 1 dietary factor during the telephone questionnaire (OR, 2.6), being overweight (OR, 1.3) or neutered (OR, 3.6), previous surgery other than neutering (OR, 21.1), and the interaction between neuter status and previous surgery other than neutering (OR, 0.1) were associated with the odds of pancreatitis. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that dietary factors, being neutered, and previous surgery other than neutering increased the odds of pancreatitis in dogs.
OBJECTIVE: To estimate associations between dietary factors and pancreatitis in dogs. Design-Retrospective case-control study. ANIMALS: 198 dogs with a clinical diagnosis of pancreatitis and 187 control dogs with a diagnosis of renal failure without clinical evidence of pancreatitis. PROCEDURES: Information on signalment, weight, body condition, dietary intake, medical history, diagnostic tests performed, concurrent diseases, treatments, duration of hospitalization, and discharge status was extracted from medical records. Information on dietary intake, signalment, weight, and medical, surgical, and environmental history was collected through a telephone questionnaire. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals. RESULTS: On the basis of information extracted from the medical record, ingesting unusual food items (OR, 4.3) increased the odds of pancreatitis. On the basis of information gathered through the telephone questionnaire, ingesting unusual food items (OR, 6.1), ingesting table scraps the week before diagnosis (OR, 2.2) or throughout life (OR, 2.2), and getting into the trash (OR, 13.2) increased the odds of pancreatitis. Multivariable modeling indicated that reporting exposure to > or = 1 dietary factor during the telephone questionnaire (OR, 2.6), being overweight (OR, 1.3) or neutered (OR, 3.6), previous surgery other than neutering (OR, 21.1), and the interaction between neuter status and previous surgery other than neutering (OR, 0.1) were associated with the odds of pancreatitis. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that dietary factors, being neutered, and previous surgery other than neutering increased the odds of pancreatitis in dogs.