Literature DB >> 18980069

Maintenance debridement in the treatment of difficult-to-heal chronic wounds. Recommendations of an expert panel.

Vincent Falanga1, Harold Brem, William J Ennis, Randall Wolcott, Lisa J Gould, Elizabeth A Ayello.   

Abstract

INTRODUCTION: Maintenance debridement has been proposed as a therapeutic intervention to address the problem of chronic wounds characterized by an adequate wound bed but absent or slow healing. A panel of experts convened to address the rationale and method of maintenance debridement.
PURPOSE: The goals of the panel were to summarize the scientific rationale for maintenance debridement, discuss the biochemical and cellular abnormalities in the wound bed, and provide a working algorithm for how maintenance debridement should be used.
METHODS: A multidisciplinary panel of wound healing and wound care experts comprising the fields of nursing, dermatology, internal medicine, and surgery was assembled to address maintenance debridement from different points of view and offer a unified approach.
FINDINGS: The chronic wound contains a number of microbial, biochemical, and cellular features and abnormalities that prevent or slow its progression to healing despite a seemingly adequate wound bed. Under these circumstances, maintenance debridement is proposed as a way to remove tissues that are colonized with an excessive bacterial burden and diminish what can be described as a biochemical and cellular burden that impairs healing. A working clinical algorithm is proposed.
CONCLUSION: Maintenance debridement is a proactive way to "jump-start" the wound and keep it in a healing mode, even when traditional debridement may not appear necessary because of a seemingly "healthy" wound bed.

Mesh:

Year:  2008        PMID: 18980069

Source DB:  PubMed          Journal:  Ostomy Wound Manage        ISSN: 0889-5899            Impact factor:   2.629


  11 in total

Review 1.  A primer on wound bed preparation.

Authors:  Chuck Gokoo
Journal:  J Am Col Certif Wound Spec       Date:  2009-05-01

2.  Skin substitutes based on allogenic fibroblasts or keratinocytes for chronic wounds not responding to conventional therapy: a retrospective observational study.

Authors:  Giorgio Pajardi; Vicenzo Rapisarda; Francesco Somalvico; Andrea Scotti; Giulia Lo Russo; Francesco Ciancio; Arturo Sgrò; Manuela Nebuloni; Raffaele Allevi; Maria L Torre; Emilio Trabucchi; Mario Marazzi
Journal:  Int Wound J       Date:  2014-02-12       Impact factor: 3.315

Review 3.  Mesenchymal Stem Cells in Chronic Wounds: The Spectrum from Basic to Advanced Therapy.

Authors:  Marta Otero-Viñas; Vincent Falanga
Journal:  Adv Wound Care (New Rochelle)       Date:  2016-04-01       Impact factor: 4.730

Review 4.  Extending the TIME concept: what have we learned in the past 10 years?(*).

Authors:  David J Leaper; Gregory Schultz; Keryln Carville; Jacqueline Fletcher; Theresa Swanson; Rebecca Drake
Journal:  Int Wound J       Date:  2012-12       Impact factor: 3.315

5.  Commercial wound dressings for the treatment of exuding wounds: an in-depth physico-chemical comparative study.

Authors:  Manon Minsart; Sandra Van Vlierberghe; Peter Dubruel; Arn Mignon
Journal:  Burns Trauma       Date:  2022-06-21

Review 6.  Optimizing Wound Bed Preparation With Collagenase Enzymatic Debridement.

Authors:  Stanley K McCallon; Dorothy Weir; John C Lantis
Journal:  J Am Coll Clin Wound Spec       Date:  2015-08-15

7.  Correlation between health-related quality of life and venous leg ulcer's severity and characteristics: a cross-sectional study.

Authors:  Héctor González de la Torre; María L Quintana-Lorenzo; Estrella Perdomo-Pérez; José Verdú
Journal:  Int Wound J       Date:  2016-04-25       Impact factor: 3.315

8.  Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants.

Authors:  Priscilla L Phillips; Qingping Yang; Stephen Davis; Edith M Sampson; John I Azeke; Afifa Hamad; Gregory S Schultz
Journal:  Int Wound J       Date:  2013-09-13       Impact factor: 3.315

9.  Hyaluronic Acid/Collagenase Ointment in the Treatment of Chronic Hard-to-Heal Wounds: An Observational and Retrospective Study.

Authors:  Francesco De Francesco; Marialuisa De Francesco; Michele Riccio
Journal:  J Clin Med       Date:  2022-01-21       Impact factor: 4.241

Review 10.  Challenges in the Treatment of Chronic Wounds.

Authors:  Robert G Frykberg; Jaminelli Banks
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-09-01       Impact factor: 4.730

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.