Literature DB >> 18979517

Non-cytotoxic protection by human NK cells in mucosal secondary lymphoid tissues.

Christian Münz1.   

Abstract

Even though NK cells have been named for their spontaneous cytotoxicity, a large subpopulation of human NK cells primarily responds to activation with cytokine secretion and not killing. These CD56brightCD16(-) NK cells are abundant in secondary lymphoid tissues, can restrict pathogens that have breached mucosal barriers, and assist Th1 polarization during immune response priming. This exciting new aspect of NK-cell biology is discussed in this viewpoint.

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Year:  2008        PMID： 18979517     DOI： 10.1002/eji.200838849

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  7 in total

1.  Regulation of human NK-cell cytokine and chemokine production by target cell recognition.

Authors:  Cyril Fauriat; Eric O Long; Hans-Gustaf Ljunggren; Yenan T Bryceson
Journal:  Blood       Date:  2009-12-01       Impact factor: 22.113

Review 2.  Alteration of the nasal responses to influenza virus by tobacco smoke.

Authors:  Terry L Noah; Haibo Zhou; Ilona Jaspers
Journal:  Curr Opin Allergy Clin Immunol       Date:  2012-02

Review 3.  Insights into NK cell biology from human genetics and disease associations.

Authors:  Stephanie M Wood; Hans-Gustaf Ljunggren; Yenan T Bryceson
Journal:  Cell Mol Life Sci       Date:  2011-08-27       Impact factor: 9.261

4.  Natural killer cell subsets and natural killer-like T-cell populations in benign and neoplastic B-cell proliferations vary based on clinicopathologic features.

Authors:  Sarah E Gibson; Steven H Swerdlow; Raymond E Felgar
Journal:  Hum Pathol       Date:  2011-02-02       Impact factor: 3.466

5.  Nasal lavage natural killer cell function is suppressed in smokers after live attenuated influenza virus.

Authors:  Katherine M Horvath; Margaret Herbst; Haibo Zhou; Hongtao Zhang; Terry L Noah; Ilona Jaspers
Journal:  Respir Res       Date:  2011-08-04

6.  Differential chemotactic receptor requirements for NK cell subset trafficking into bone marrow.

Authors:  Giovanni Bernardini; Giuseppe Sciumè; Angela Santoni
Journal:  Front Immunol       Date:  2013-01-30       Impact factor: 7.561

Review 7.  Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity.

Authors:  Hyoungjun Ham; Daniel D Billadeau
Journal:  Front Immunol       Date:  2014-01-21       Impact factor: 7.561
  7 in total

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