Literature DB >> 18979144

Does CT influence the decision to perform colectomy in patients with severe ulcerative colitis?

Andre da Luz Moreira1, Jon D Vogel, Mark Baker, Isabella Mor, Ren Zhang, Victor Fazio.   

Abstract

PURPOSE: The purpose of this study was to evaluate the impact of abdominal computerized tomography (CT) on the decision to perform colectomy in patients with severe acute ulcerative colitis (SAC).
METHODS: Patients with SAC admitted to a single hospital between 2002 and 2007 were reviewed. The criteria for SAC were > or =6 bloody bowel movements per day plus fever >37.8 degrees C, pulse >90, or hemoglobin <10.5 g/dL. Study patients were given a SAC score of 2-4 based on these criteria. Clinical and laboratory parameters, medication use, abdominal X-ray, and endoscopic findings in SAC patients who did or did not have an abdominal CT were compared. Chi-squared, Fisher exact test, and Wilcoxon rank sum test were used as appropriate.
RESULTS: Ninety-two consecutive patients with SAC were evaluated. CT was performed in 26 (28%). The SAC score, laboratory values, abdominal X-ray, and endoscopic findings were similar in patients who did or did not have a CT. Colectomy was performed in 32 (48%) and 10 (38%) patients who did or did not have a CT, respectively (p = 0.4). The CT findings were similar in patients who required colectomy and those who did not require colectomy. In two (8%) of the patients who underwent CT, the CT findings clearly influenced the decision to perform or defer colectomy.
CONCLUSION: CT has a minor impact on the decision to perform colectomy in patients with severe acute ulcerative colitis.

Entities:  

Mesh:

Year:  2008        PMID: 18979144     DOI: 10.1007/s11605-008-0732-3

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  24 in total

1.  Computed tomography severity index is an early prognostic tool for acute pancreatitis.

Authors:  Patrick W Vriens; Pieter van de Linde; Eveline T Slotema; Piet E Warmerdam; Paul J Breslau
Journal:  J Am Coll Surg       Date:  2005-10       Impact factor: 6.113

2.  Infliximab for induction and maintenance therapy for ulcerative colitis.

Authors:  Paul Rutgeerts; William J Sandborn; Brian G Feagan; Walter Reinisch; Allan Olson; Jewel Johanns; Suzanne Travers; Daniel Rachmilewitz; Stephen B Hanauer; Gary R Lichtenstein; Willem J S de Villiers; Daniel Present; Bruce E Sands; Jean Frédéric Colombel
Journal:  N Engl J Med       Date:  2005-12-08       Impact factor: 91.245

3.  Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study.

Authors:  K W Schroeder; W J Tremaine; D M Ilstrup
Journal:  N Engl J Med       Date:  1987-12-24       Impact factor: 91.245

4.  Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial.

Authors:  G Van Assche; W J Sandborn; B G Feagan; B A Salzberg; D Silvers; P S Monroe; W M Pandak; F H Anderson; J F Valentine; G E Wild; D J Geenen; R Sprague; S R Targan; P Rutgeerts; V Vexler; D Young; R S Shames
Journal:  Gut       Date:  2006-04-07       Impact factor: 23.059

5.  Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis.

Authors:  Gert Van Assche; Geert D'Haens; Maja Noman; Séverine Vermeire; Martin Hiele; Katrien Asnong; Joris Arts; Andre D'Hoore; Freddy Penninckx; Paul Rutgeerts
Journal:  Gastroenterology       Date:  2003-10       Impact factor: 22.682

6.  A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.

Authors:  H Ogata; T Matsui; M Nakamura; M Iida; M Takazoe; Y Suzuki; T Hibi
Journal:  Gut       Date:  2006-02-16       Impact factor: 23.059

7.  Colonoscopy of acute colitis. A safe and reliable tool for assessment of severity.

Authors:  F Carbonnel; A Lavergne; M Lémann; A Bitoun; P Valleur; P Hautefeuille; A Galian; R Modigliani; J C Rambaud
Journal:  Dig Dis Sci       Date:  1994-07       Impact factor: 3.199

8.  CT enterography for Crohn's disease: accurate preoperative diagnostic imaging.

Authors:  Jon Vogel; Andre da Luz Moreira; Mark Baker; Jeffery Hammel; David Einstein; Luca Stocchi; Victor Fazio
Journal:  Dis Colon Rectum       Date:  2007-11       Impact factor: 4.585

9.  Intensive intravenous treatment of ulcerative colitis.

Authors:  G Järnerot; P Rolny; H Sandberg-Gertzén
Journal:  Gastroenterology       Date:  1985-11       Impact factor: 22.682

10.  Infliximab in moderately severe glucocorticoid resistant ulcerative colitis: a randomised controlled trial.

Authors:  C S J Probert; S D Hearing; S Schreiber; T Kühbacher; S Ghosh; I D R Arnott; A Forbes
Journal:  Gut       Date:  2003-07       Impact factor: 23.059

View more
  1 in total

1.  CT-Visualized Colonic Mural Stratification Independently Predicts the Need for Medical or Surgical Rescue Therapy in Hospitalized Ulcerative Colitis Patients.

Authors:  Kelly C Cushing; Hamed Kordbacheh; Michael S Gee; Avinash Kambadakone; Ashwin N Ananthakrishnan
Journal:  Dig Dis Sci       Date:  2019-02-22       Impact factor: 3.199

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.