| Literature DB >> 18977042 |
Mitsunori Nishikawa1, Tomoko Tanaka1, Kazumitsu Nakashima1, Kazuyoshi Senda1, Masataka Shibasaki1, Hisayuki Miura2, Akiko Tamakoshi3, Toshiki Ohta2, Tetsuya Yagi4.
Abstract
Our objective is to identify risk factors for carriage of MRSA on admission to a geriatric hospital where MRSA is endemic. A prospective screening for MRSA carriage was conducted by swabbing anterior nares and anal skin for 6 weeks. One hundred and thirty-eight patients aged over 65 were enrolled after obtaining their informed consent. Swabs of anterior nares and anal skin of patients were submitted for culture for MRSA. The demographic, administrative, and clinical data for each participant were recorded, and their association with MRSA carriage was determined by stepwise regression analysis. MRSA was recovered from 11 patients (11/138 patients, 8.0%), and from anal skin in 8 of them. Without screening of anal skin, 5 out of 11 carriers had been missed. Multivariate analysis revealed that hypoalbuminemia (adjusted risk ratio, RR=6.39, 95% confidence interval, CI=1.08-37.84) and bedridden status (RR=8.26, CI=1.04-65.31) were independent risk factors. Screening of elderly patients for gastrointestinal colonization on admission had implications for early detection of the reservoir of MRSA. Systematic selective screening for MRSA carriage targeting high-risk patients with hypoalbuminemia or bedridden status would be useful for infection control of this resistant organism.Entities:
Mesh：
Year: 2008 PMID： 18977042 DOI： 10.1016/j.archger.2008.08.012
Source DB: PubMed Journal: Arch Gerontol Geriatr ISSN： 0167-4943 Impact factor: 3.250