Literature DB >> 18976446

Association of IL-6 gene polymorphism with the outcome of allogeneic haematopoietic stem cell transplantation in Czech patients.

Z Ambruzova1, F Mrazek, L Raida, E Faber, J Onderkova, E Kriegova, K Indrak, M Petrek.   

Abstract

Interleukin-6 (IL-6) is an important pro-inflammatory mediator implicated in immune-mediated complications of allogeneic haematopoietic stem cell transplantation (aHSCT). In accord with previous reports, this preliminary study on 56 donor-recipient pairs revealed IL-6-174 single nucleotide polymorphisms as a risk factor for the development of acute graft-versus-host disease and decreased survival after aHSCT.

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Year:  2008        PMID： 18976446     DOI： 10.1111/j.1744-313X.2008.00798.x

Source DB:  PubMed          Journal:  Int J Immunogenet        ISSN： 1744-3121            Impact factor:   1.466


  5 in total

1.  Replication and validation of genetic polymorphisms associated with survival after allogeneic blood or marrow transplant.

Authors:  Ezgi Karaesmen; Abbas A Rizvi; Leah M Preus; Philip L McCarthy; Marcelo C Pasquini; Kenan Onel; Xiaochun Zhu; Stephen Spellman; Christopher A Haiman; Daniel O Stram; Loreall Pooler; Xin Sheng; Qianqian Zhu; Li Yan; Qian Liu; Qiang Hu; Amy Webb; Guy Brock; Alyssa I Clay-Gilmour; Sebastiano Battaglia; David Tritchler; Song Liu; Theresa Hahn; Lara E Sucheston-Campbell
Journal:  Blood       Date:  2017-08-15       Impact factor: 22.113

2.  Analysis of a Genetic Polymorphism in the Costimulatory Molecule TNFSF4 with Hematopoietic Stem Cell Transplant Outcomes.

Authors:  Peter T Jindra; Susan E Conway; Stacy M Ricklefs; Stephen F Porcella; Sarah L Anzick; Mike Haagenson; Tao Wang; Stephen Spellman; Edgar Milford; Peter Kraft; David H McDermott; Reza Abdi
Journal:  Biol Blood Marrow Transplant       Date:  2015-09-05       Impact factor: 5.742

Review 3.  Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target.

Authors:  Tor Henrik Anderson Tvedt; Elisabeth Ersvaer; Anders Aune Tveita; Øystein Bruserud
Journal:  Front Immunol       Date:  2017-06-08       Impact factor: 7.561

Review 4.  Graft versus Host Disease: From Basic Pathogenic Principles to DNA Damage Response and Cellular Senescence.

Authors:  Adam Kuba; Ludek Raida
Journal:  Mediators Inflamm       Date:  2018-03-26       Impact factor: 4.711

5.  Association of recipient and donor interleukin 6 polymorphisms 174 and 597 with outcome after allogeneic hematopoietic stem cell transplantation in children.

Authors:  Laura Wetzel; Susan Wittig; Bernd Gruhn
Journal:  J Cancer Res Clin Oncol       Date:  2021-06-12       Impact factor: 4.553
  5 in total

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