Literature DB >> 18975868

New strategy for quantifying biological zinc by a modified zinpyr fluorescence sensor.

Xiao-an Zhang1, Dugan Hayes, Sarah J Smith, Simone Friedle, Stephen J Lippard.   

Abstract

Substitution of one pyridine by pyrazine in each DPA appendage of ZP1 leads to a new zinc sensor, ZPP1, with a modified background fluorescence and zinc affinity. ZPP1 exhibits a two-step zinc response during fluorescence titrations, which leads to a new method for zinc quantification. The ability of ZPP1 to image and quantify zinc was demonstrated in pancreatic Min6 cells.

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Year:  2008        PMID： 18975868      PMCID： PMC2645955          DOI： 10.1021/ja807156b

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  9 in total

1.  Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicator.

Authors:  Kyle R Gee; Zhang-Lin Zhou; Wei-Jun Qian; Robert Kennedy
Journal:  J Am Chem Soc       Date:  2002-02-06       Impact factor: 15.419

2.  Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc.

Authors:  Christopher J Chang; Elizabeth M Nolan; Jacek Jaworski; Shawn C Burdette; Morgan Sheng; Stephen J Lippard
Journal:  Chem Biol       Date:  2004-02

Review 3.  Zinc sensing for cellular application.

Authors:  Kazuya Kikuchi; Kensuke Komatsu; Tetsuo Nagano
Journal:  Curr Opin Chem Biol       Date:  2004-04       Impact factor: 8.822

4.  Zinc influx and physiological consequences in the beta-insulinoma cell line, Min6.

Authors:  Tsvia Priel; Michal Hershfinkel
Journal:  Biochem Biophys Res Commun       Date:  2006-05-24       Impact factor: 3.575

Review 5.  Zinc, the pancreas, and diabetes: insights from rodent studies and future directions.

Authors:  Carla G Taylor
Journal:  Biometals       Date:  2005-08       Impact factor: 2.949

Review 6.  The neurobiology of zinc in health and disease.

Authors:  Christopher J Frederickson; Jae-Young Koh; Ashley I Bush
Journal:  Nat Rev Neurosci       Date:  2005-06       Impact factor: 34.870

7.  Studies in the imidazo(1,5-a)pyrazine system.

Authors:  E Abushanab; A P Bindra; L Goodman; H Peterson
Journal:  J Org Chem       Date:  1973-06-01       Impact factor: 4.354

Review 8.  The biochemical basis of zinc physiology.

Authors:  B L Vallee; K H Falchuk
Journal:  Physiol Rev       Date:  1993-01       Impact factor: 37.312

9.  Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution.

Authors:  S C Burdette; G K Walkup; B Spingler; R Y Tsien; S J Lippard
Journal:  J Am Chem Soc       Date:  2001-08-15       Impact factor: 15.419
  9 in total
  36 in total

1.  Illuminating mobile zinc with fluorescence from cuvettes to live cells and tissues.

Authors:  Zhen Huang; Stephen J Lippard
Journal:  Methods Enzymol       Date:  2012       Impact factor: 1.600

Review 2.  Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors.

Authors:  Michael D Pluth; Elisa Tomat; Stephen J Lippard
Journal:  Annu Rev Biochem       Date:  2011       Impact factor: 23.643

3.  Understanding zinc quantification with existing and advanced ditopic fluorescent Zinpyr sensors.

Authors:  Daniela Buccella; Joshua A Horowitz; Stephen J Lippard
Journal:  J Am Chem Soc       Date:  2011-02-25       Impact factor: 15.419

4.  Zn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ions.

Authors:  Lei Zhu; Zhao Yuan; J Tyler Simmons; Kesavapillai Sreenath
Journal:  RSC Adv       Date:  2014-01-01       Impact factor: 3.361

Review 5.  Fluorescent sensors for measuring metal ions in living systems.

Authors:  Kyle P Carter; Alexandra M Young; Amy E Palmer
Journal:  Chem Rev       Date:  2014-03-03       Impact factor: 60.622

6.  SpiroZin1: a reversible and pH-Insensitive, reaction-based, red-fluorescent probe for imaging biological mobile zinc.

Authors:  Pablo Rivera-Fuentes; Stephen J Lippard
Journal:  ChemMedChem       Date:  2014-03-11       Impact factor: 3.466

7.  Zinc as an Imaging Biomarker of Prostate Cancer.

Authors:  Su-Tang Lo; André F Martins; Veronica Clavijo Jordan; A Dean Sherry
Journal:  Isr J Chem       Date:  2017-07-31       Impact factor: 3.333

8.  Tris(2-pyridylmethyl)amine (TPA) as a membrane-permeable chelator for interception of biological mobile zinc.

Authors:  Zhen Huang; Xiao-an Zhang; Miquel Bosch; Sarah J Smith; Stephen J Lippard
Journal:  Metallomics       Date:  2013-06       Impact factor: 4.526

9.  Subtle modification of 2,2-dipicolylamine lowers the affinity and improves the turn-on of Zn(II)-selective fluorescent sensors.

Authors:  Brian A Wong; Simone Friedle; Stephen J Lippard
Journal:  Inorg Chem       Date:  2009-08-03       Impact factor: 5.165

10.  Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn2+ sensors.

Authors:  Brian A Wong; Simone Friedle; Stephen J Lippard
Journal:  J Am Chem Soc       Date:  2009-05-27       Impact factor: 15.419
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