Literature DB >> 18975152

Anticomplementary activity of ergosterol peroxide fromNaematoloma fasciculare and reassignment of NMR data.

D S Kim1, N I Baek, S R Oh, K Y Jung, I S Lee, J H Kim, H K Lee.   

Abstract

A very high content (at least 0.23%) of ergosterol peroxide was isolated fromNaematoloma fasciculare Karst. Not only ergosterol peroxide but also ergosterol showed very strong anticomplementary activity on the classical pathway, the IC(50) values being 5.0 muM and 1.0 muM, respectively. The(1)H and(13)C NMR data of ergosterol peroxide were revised and completely assigned by DEPT,(1)H-(1)H COSY, HMQC and HMBC correlations.

Entities:  

Year:  1997        PMID： 18975152     DOI： 10.1007/BF02976145

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  4 in total

1.  Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.

Authors:  Navdar Sever; Randall K Mann; Libin Xu; William J Snell; Carmen I Hernandez-Lara; Ned A Porter; Philip A Beachy
Journal:  Proc Natl Acad Sci U S A       Date:  2016-05-09       Impact factor: 11.205

2.  Syntheses and biological activity studies of novel sterol analogs from nitroso Diels-Alder reactions of ergosterol.

Authors:  Baiyuan Yang; Patricia A Miller; Ute Möllmann; Marvin J Miller
Journal:  Org Lett       Date:  2009-07-02       Impact factor: 6.005

3.  Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells.

Authors:  Yun-Hee Rhee; Soo-Jin Jeong; Hyo-Jeong Lee; Hyo-Jung Lee; Wonil Koh; Ji Hoon Jung; Sun-Hee Kim; Kim Sung-Hoon
Journal:  BMC Cancer       Date:  2012-01-20       Impact factor: 4.430

4.  Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua).

Authors:  Supawadee Parhira; Guo-Yuan Zhu; Ting Li; Liang Liu; Li-Ping Bai; Zhi-Hong Jiang
Journal:  Chin Med       Date:  2016-03-02       Impact factor: 5.455
  4 in total

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