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Literature DB >> 18974747

Romiplostim.

Douglas B Cines¹, Uma Yasothan, Peter Kirkpatrick.

Abstract

In August 2008, romiplostim (Nplate; Amgen), a thrombopoietin receptor agonist, was approved by the US FDA for the treatment of thrombocytopaenia in patients with chronic immune thrombocytopaenic purpura who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy.

Entities: Disease Species

Mesh：

Substances：

Year: 2008 PMID： 18974747 DOI： 10.1038/nrd2741

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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Cited

13 in total

1. In vitro selection of a peptide antagonist of growth hormone secretagogue receptor using cDNA display.

Authors: Shingo Ueno; Sayaka Yoshida; Anupom Mondal; Kazuya Nishina; Makoto Koyama; Ichiro Sakata; Kenju Miura; Yujiro Hayashi; Naoto Nemoto; Koichi Nishigaki; Takafumi Sakai
Journal: Proc Natl Acad Sci U S A Date: 2012-06-20 Impact factor: 11.205

Review 2. Combinatorial peptide libraries: mining for cell-binding peptides.

Authors: Bethany Powell Gray; Kathlynn C Brown
Journal: Chem Rev Date: 2013-12-03 Impact factor: 60.622

3. Eltrombopag, a potent stimulator of megakaryopoiesis.

Authors: Hana Raslova; William Vainchenker; Isabelle Plo
Journal: Haematologica Date: 2016-12 Impact factor: 9.941

Review 4. Pharmacokinetics of recombinant bifunctional fusion proteins.

Authors: Xiaoying Chen; Jennica L Zaro; Wei-Chiang Shen
Journal: Expert Opin Drug Metab Toxicol Date: 2012-03-20 Impact factor: 4.481

5. Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs.

Authors: Jennifer A Dumont; Tongyao Liu; Susan C Low; Xin Zhang; George Kamphaus; Paul Sakorafas; Cara Fraley; Douglas Drager; Thomas Reidy; Justin McCue; Helen W G Franck; Elizabeth P Merricks; Timothy C Nichols; Alan J Bitonti; Glenn F Pierce; Haiyan Jiang
Journal: Blood Date: 2012-01-13 Impact factor: 22.113

Romiplostim.

1. In vitro selection of a peptide antagonist of growth hormone secretagogue receptor using cDNA display.

Review 2. Combinatorial peptide libraries: mining for cell-binding peptides.

3. Eltrombopag, a potent stimulator of megakaryopoiesis.

Review 4. Pharmacokinetics of recombinant bifunctional fusion proteins.

5. Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs.

Review 6. Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications.

7. A review of immune thrombocytopenic purpura: focus on the novel thrombopoietin agonists.

8. Expression, purification and biological activity assessment of romiplostim biosimilar peptibody.

Review 9. Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.

Review 10. Exogenous endothelial cells as accelerators of hematopoietic reconstitution.