| Literature DB >> 18973879 |
Daniel S Seidman1, Alek Itsekson, Michael Alesker, Mati Zolti, Howard Carp, Igal Wolman.
Abstract
We used an in vivo rat model to demonstrate that low-dose intradermal exposure to E(2) valerate has an inverse effect on the female's estrus cycle pattern and can significantly reduce litter size. These results suggest that, under certain circumstances, environmental exposure to exogenous estrogens may play a role as an endocrine disruptor and adversely affect reproductive outcome.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18973879 DOI： 10.1016/j.fertnstert.2008.08.018
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329