Literature DB >> 18972618

Lymphocyte subset reconstitution in pediatric liver recipients induced with steroid-free rabbit anti-human thymocyte globulin.

Anjan Talukdar1, Chethan AshokKumar, Jennifer Farrar, Patrick Wilson, Arun Janakiramanan, Mary Tregaskes, Rakesh Sindhi.   

Abstract

Multiple measurements of lymphocyte subsets in 91 children treated with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic cells, and gradual reconstitution of all other subsets, which is complete after one yr. Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence.

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Year:  2008        PMID： 18972618      PMCID： PMC2943864          DOI： 10.1111/j.1399-3046.2007.00797.x

Source DB:  PubMed          Journal:  Pediatr Transplant        ISSN： 1397-3142


  15 in total

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Authors:  R Calne
Journal:  Transplant Proc       Date:  2000-11       Impact factor: 1.066

2.  Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy.

Authors:  S John Swanson; Douglas A Hale; Roslyn B Mannon; David E Kleiner; Linda C Cendales; Christine E Chamberlain; Shirley M Polly; David M Harlan; Allan D Kirk
Journal:  Lancet       Date:  2002-11-23       Impact factor: 79.321

3.  Tolerogenic immunosuppression for organ transplantation.

Authors:  Thomas E Starzl; Noriko Murase; Kareem Abu-Elmagd; Edward A Gray; Ron Shapiro; Bijan Eghtesad; Robert J Corry; Mark L Jordan; Paulo Fontes; Tim Gayowski; Geoffrey Bond; Velma P Scantlebury; Santosh Potdar; Parmjeet Randhawa; Tong Wu; Adriana Zeevi; Michael A Nalesnik; Jennifer Woodward; Amadeo Marcos; Massimo Trucco; Anthony J Demetris; John J Fung
Journal:  Lancet       Date:  2003-05-03       Impact factor: 79.321

4.  T cell subset analysis by flow cytometry during MALG induction for pediatric renal transplantation.

Authors:  T E Buchman; D B Kershaw; R M Merion; J M Ham; A B Sedman; M B Walter; R C Kelsch
Journal:  Transplantation       Date:  1993-05       Impact factor: 4.939

5.  Enhanced donor-specific alloreactivity occurs independently of immunosuppression in children with early liver rejection.

Authors:  Rakesh Sindhi; Amy Magill; Carol Bentlejewski; Ali Abdullah; Mary Tresgaskes; Joseph Seward; Janine Janosky; Adriana Zeevi
Journal:  Am J Transplant       Date:  2005-01       Impact factor: 8.086

6.  Persistent donor-specific alloreactivity may portend delayed liver rejection during drug minimization in children.

Authors:  Nandita Khera; Janine Janosky; Adriana Zeevi; George Mazariegos; Amadeo Marcos; Rakesh Sindhi
Journal:  Front Biosci       Date:  2007-01-01

7.  Phenotypic changes in lymphocyte subpopulations in pediatric renal-transplant patients after T-cell depletion.

Authors:  Günter Klaus; Katharina Mostert; Barbara Reckzeh; Thomas F Mueller
Journal:  Transplantation       Date:  2003-12-27       Impact factor: 4.939

8.  Thymoglobuline use in pediatric heart transplantation.

Authors:  F Parisi; H Danesi; C Squitieri; L Di Chiara; L Ravà; R M Di Donato
Journal:  J Heart Lung Transplant       Date:  2003-05       Impact factor: 10.247

9.  Polyclonal antithymocyte serum: immune prophylaxis and rejection therapy in pediatric heart transplantation patients.

Authors:  L K Lebeck; L Chang; C Lopez-McCormack; R Chinnock; M Boucek
Journal:  J Heart Lung Transplant       Date:  1993 Nov-Dec       Impact factor: 10.247

10.  Posttransplant lymphoproliferative disorders in liver transplantation: a 20-year experience.

Authors:  Ashok Jain; Mike Nalesnik; Jorge Reyes; Renu Pokharna; George Mazariegos; Michael Green; Bijan Eghtesad; Wallis Marsh; Thomas Cacciarelli; Paulo Fontes; Kareem Abu-Elmagd; Rakesh Sindhi; Jake Demetris; John Fung
Journal:  Ann Surg       Date:  2002-10       Impact factor: 12.969
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  4 in total

1.  Antithymocyte globulin facilitates alloreactive T-cell apoptosis by means of caspase-3: potential implications for monitoring rejection-free outcomes.

Authors:  Chethan Ashokkumar; Qing Sun; Mylarappa Ningappa; Brandon W Higgs; George Mazariegos; Adriana Zeevi; Rakesh Sindhi
Journal:  Transplantation       Date:  2015-01       Impact factor: 4.939

2.  Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection.

Authors:  Rakesh Sindhi; Brandon W Higgs; Daniel E Weeks; Chethan Ashokkumar; Ronald Jaffe; Cecilia Kim; Patrick Wilson; Nydia Chien; Joseph Glessner; Anjan Talukdar; George Mazariegos; M Michael Barmada; Edward Frackleton; Nancy Petro; Andrew Eckert; Hakon Hakonarson; Robert Ferrell
Journal:  Gastroenterology       Date:  2008-06-03       Impact factor: 22.682

3.  Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection.

Authors:  M Ningappa; C Ashokkumar; B W Higgs; Q Sun; R Jaffe; G Mazariegos; D Li; D E Weeks; S Subramaniam; R Ferrell; H Hakonarson; R Sindhi
Journal:  Am J Transplant       Date:  2015-12-11       Impact factor: 8.086

4.  Alloreactive CD154-expressing T-cell subsets with differential sensitivity to the immunosuppressant, belatacept: potential targets of novel belatacept-based regimens.

Authors:  Chethan Ashokkumar; Bishu Ganguly; Robert Townsend; Jaimie White; Samantha Levy; Michael Moritz; George Mazariegos; Qing Sun; Rakesh Sindhi
Journal:  Sci Rep       Date:  2015-10-16       Impact factor: 4.379
  4 in total

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