Literature DB >> 1896511

Lesions of the suprachiasmatic nucleus disrupt circadian locomotor rhythms in the mouse.

W J Schwartz1, P Zimmerman.   

Abstract

Entrained and free-running rhythms of wheel-running activity were recorded in male BALB/cByJ mice with electrolytic lesions of the suprachiasmatic nucleus (SCN), site of a circadian pacemaker in mammals. Complete ablation of the nucleus abolished the circadian locomotor rhythm; in some cases, wheel-running was synchronized by a light-dark cycle, but the phase relationship of this activity to the cycle was often aberrant. Unilateral lesions or those missing the SCN did not eliminate rhythmicity.

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Year:  1991        PMID: 1896511     DOI: 10.1016/0031-9384(91)90364-t

Source DB:  PubMed          Journal:  Physiol Behav        ISSN: 0031-9384


  20 in total

1.  PML regulates PER2 nuclear localization and circadian function.

Authors:  Takao Miki; Zhixiang Xu; Misty Chen-Goodspeed; Mingguang Liu; Anita Van Oort-Jansen; Michael A Rea; Zhaoyang Zhao; Cheng Chi Lee; Kun-Sang Chang
Journal:  EMBO J       Date:  2012-01-24       Impact factor: 11.598

2.  Learned motivation drives circadian physiology in the absence of the master circadian clock.

Authors:  Oliver Rawashdeh; Shannon J Clough; Randall L Hudson; Margarita L Dubocovich
Journal:  FASEB J       Date:  2016-10-12       Impact factor: 5.191

3.  Role of neural cell adhesion molecule and polysialic acid in mouse circadian clock function.

Authors:  H Shen; M Watanabe; H Tomasiewicz; U Rutishauser; T Magnuson; J D Glass
Journal:  J Neurosci       Date:  1997-07-01       Impact factor: 6.167

4.  I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.

Authors:  Daniel Granados-Fuentes; Aaron J Norris; Yarimar Carrasquillo; Jeanne M Nerbonne; Erik D Herzog
Journal:  J Neurosci       Date:  2012-07-18       Impact factor: 6.167

Review 5.  Sleep and circadian disruption and incident breast cancer risk: An evidence-based and theoretical review.

Authors:  Laura B Samuelsson; Dana H Bovbjerg; Kathryn A Roecklein; Martica H Hall
Journal:  Neurosci Biobehav Rev       Date:  2017-10-13       Impact factor: 8.989

6.  Circadian rhythms in the mouse reproductive axis during the estrous cycle and pregnancy.

Authors:  Alexandra M Yaw; Thu V Duong; Duong Nguyen; Hanne M Hoffmann
Journal:  J Neurosci Res       Date:  2020-03-03       Impact factor: 4.164

Review 7.  Clocks on top: the role of the circadian clock in the hypothalamic and pituitary regulation of endocrine physiology.

Authors:  Karen J Tonsfeldt; Patrick E Chappell
Journal:  Mol Cell Endocrinol       Date:  2011-07-20       Impact factor: 4.102

8.  The diurnal oscillation of MAP (mitogen-activated protein) kinase and adenylyl cyclase activities in the hippocampus depends on the suprachiasmatic nucleus.

Authors:  Trongha X Phan; Trongha H Phan; Guy C-K Chan; Carlos B Sindreu; Kristin L Eckel-Mahan; Daniel R Storm
Journal:  J Neurosci       Date:  2011-07-20       Impact factor: 6.167

9.  Disruption of masking by hypothalamic lesions in Syrian hamsters.

Authors:  Xiaodong Li; Jenifer Gilbert; Fred C Davis
Journal:  J Comp Physiol A Neuroethol Sens Neural Behav Physiol       Date:  2004-09-24       Impact factor: 1.836

10.  Mop3 is an essential component of the master circadian pacemaker in mammals.

Authors:  M K Bunger; L D Wilsbacher; S M Moran; C Clendenin; L A Radcliffe; J B Hogenesch; M C Simon; J S Takahashi; C A Bradfield
Journal:  Cell       Date:  2000-12-22       Impact factor: 41.582

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