| Literature DB >> 1896511 |
Abstract
Entrained and free-running rhythms of wheel-running activity were recorded in male BALB/cByJ mice with electrolytic lesions of the suprachiasmatic nucleus (SCN), site of a circadian pacemaker in mammals. Complete ablation of the nucleus abolished the circadian locomotor rhythm; in some cases, wheel-running was synchronized by a light-dark cycle, but the phase relationship of this activity to the cycle was often aberrant. Unilateral lesions or those missing the SCN did not eliminate rhythmicity.Entities:
Mesh:
Year: 1991 PMID: 1896511 DOI: 10.1016/0031-9384(91)90364-t
Source DB: PubMed Journal: Physiol Behav ISSN: 0031-9384