Literature DB >> 18964782

Spectrophotometric determination of amoxycillin and clavulanic acid in pharmaceutical preparation.

E M Abdel-Moety1, M A Abounassif, M E Mohamed, N A Khattab.   

Abstract

A spectrophotometric procedure for the simultaneous determination of amoxycillin and clavulanic acid in some pharmaceutical preparations has been developed. As the absorption bands of amoxycillin (274 and 227 nm) and clavulanic acid (270 nm) overlap, both Vierordt's method and derivative spectrophotometry have been investigated and evaluated. The first-derivative spectrophotometric method was found to be more accurate, direct and reproducible.

Entities:  

Year:  1989        PMID: 18964782     DOI: 10.1016/0039-9140(89)80265-6

Source DB:  PubMed          Journal:  Talanta        ISSN: 0039-9140            Impact factor:   6.057


  1 in total

1.  Comparative Study of RP-HPLC and UV Spectrophotometric Techniques for the Simultaneous Determination of Amoxicillin and Cloxacillin in Capsules.

Authors:  Do T Giang; Vu D Hoang
Journal:  J Young Pharm       Date:  2010-04
  1 in total

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