Literature DB >> 18964536

Complexometric-spectrophotometric assay of tetracyclines in drug formulations.

S M Sultan1, I Z Alzamil, N A Alarfaj.   

Abstract

An accurate, rapid and very simple spectrophotometric method for the assay of tetracyclines (tetracycline.HCl, chlorotetracycline.HCl, demeclocycline, oxytetracycline.HCl and doxycycline) has been developed. The method is based on the complexation of iron(III) with tetracyclines in 0.001M sulphuric acid. It has been successfully applied to the assay of tetracyclines in drug formulations, and the interferences of excipients have been examined. The results have been statistically compared with those obtained by two standard methods and found to be very satisfactory.

Entities:  

Year:  1988        PMID: 18964536     DOI: 10.1016/0039-9140(88)80030-4

Source DB:  PubMed          Journal:  Talanta        ISSN: 0039-9140            Impact factor:   6.057


  2 in total

1.  Europium-sensitized chemiluminescence of system tetracycline-H2O2-Fe(II)/(III) and its application to the determination of tetracycline.

Authors:  M Kaczmarek; A Idzikowska; S Lis
Journal:  J Fluoresc       Date:  2008-05-04       Impact factor: 2.217

2.  Determination of Tetracycline in Pharmaceutical Preparation by Molecular and Atomic Absorption Spectrophotometry and High Performance Liquid Chromatography via Complex Formation with Au(III) and Hg(II) Ions in Solutions.

Authors:  Ahlam Jameel Abdulghani; Hadi Hassan Jasim; Abbas Shebeeb Hassan
Journal:  Int J Anal Chem       Date:  2013-06-18       Impact factor: 1.885

  2 in total

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