The determination of formation constants of weak complexes by potentiometric measurements: experimental procedures and calculation methods.

Experimental and calculation procedures for the study of weak complexes by the pH-measurement technique are described. An algorithm for the calculation of formation constants, together with a computer program in FORTRAN and BASIC versions, is reported. The problems of studying weak interactions are discussed. Simulated titration curves and experimental data for K(+)-thiodiacetate complexation were used to check the proposed method.