Literature DB >> 18958433

[Ethylene glycol intoxication. Important differential diagnosis in comatose patients with metabolic acidosis].

R Müller1, J Planck, T Heveling.   

Abstract

Ethylene glycol is an alcohol, which is mainly used as antifreeze. Intoxication with ethylene glycol can cause neurological and cardiopulmonary symptoms, metabolic acidosis and acute renal failure. Therapeutic options include reversal of metabolic acidosis, inhibition of alcohol dehydrogenase and early hemodialysis. In survivors of the acute phase, lasting damage is rare. The case of a 49-year-old patient with ethylene glycol intoxication is reported which was characterized by progressive impairment of consciousness, tetraparesis, hyperventilation and metabolic acidosis.

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Year:  2009        PMID: 18958433     DOI: 10.1007/s00101-008-1460-5

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  3 in total

Review 1.  The other alcohols. Methanol, ethylene glycol, and isopropanol.

Authors:  K K Burkhart; K W Kulig
Journal:  Emerg Med Clin North Am       Date:  1990-11       Impact factor: 2.264

2.  Survival of ethylene glycol poisoning with profound acidemia.

Authors:  K R Blakeley; S E Rinner; J P Knochel
Journal:  N Engl J Med       Date:  1993-02-18       Impact factor: 91.245

3.  American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee.

Authors:  D G Barceloux; E P Krenzelok; K Olson; W Watson
Journal:  J Toxicol Clin Toxicol       Date:  1999
  3 in total

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