| Literature DB >> 18957211 |
Rachel D Groth1, Richard W Tsien.
Abstract
Prolonged changes in neuronal activity trigger compensatory modifications in synaptic function to restore firing rates to normal levels. In this issue of Neuron, Aoto et al. demonstrate that synthesis of retinoic acid offsets chronic network inactivity by increasing synaptic strength through upregulation of GluR1 receptors.Entities:
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Year: 2008 PMID： 18957211 PMCID： PMC2712292 DOI： 10.1016/j.neuron.2008.10.003
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173