Literature DB >> 18956816

[Malaria in health centres in the southern districts of Brazzaville, Congo].

M Ndounga1, P N Casimiro, V Miakassissa-Mpassi, D Loumouamou, F Ntoumi, L K Basco.   

Abstract

During the surveys on antimalarial drug efficacy carried out from 2003 to 2006, we systematically checked the presence of Plasmodium falciparum in patients consulting in two health centres located in the south of Brazzaville. The first centre is situated in the urban zone; the second, in the semi rural area. The objective of this survey was to determine the prevalence of malaria-infected patients among the consulting patients and the prevalence of symptomatic patients with acute malaria attacks based on the parasitic density. Patients with parasites were assigned to one of the 5 following classifications: <2000, > or =2000, <5000, > or =5000 and > or =10,000 asexual parasites/microl of blood. Based on the threshold of parasite density 10,000 asexual parasites/microl, 10% and 24% of febrile patients in Tenrikyo and Madibou health centres were diagnosed as cases of malaria, respectively; 13.6% and 26.8% of patients under 5 years old consulting in these two health centres had malaria attacks. If the threshold of parasite density is lowered to 2000 asexual parasites/microl for patients > or =15 years old, 8% and 14% of adults in Tenrikyo and Madibou had malaria attacks, respectively The malaria burden was higher in the periphery of the city of Brazzaville than in the urbanized central districts. The Madibou health centre located in semi rural zone receives twice as many malaria cases for consultation than Tenrikyo located in the urban zone.

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Year:  2008        PMID: 18956816     DOI: 10.3185/pathexo3111

Source DB:  PubMed          Journal:  Bull Soc Pathol Exot        ISSN: 0037-9085


  8 in total

1.  Plasmodium falciparum: differential selection of drug resistance alleles in contiguous urban and peri-urban areas of Brazzaville, Republic of Congo.

Authors:  Yoko Tsumori; Mathieu Ndounga; Toshihiko Sunahara; Nozomi Hayashida; Megumi Inoue; Shusuke Nakazawa; Prisca Casimiro; Rie Isozumi; Haruki Uemura; Kazuyuki Tanabe; Osamu Kaneko; Richard Culleton
Journal:  PLoS One       Date:  2011-08-15       Impact factor: 3.240

2.  Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study.

Authors:  Mathieu Ndounga; Prisca Nadine Casimiro; Félix Koukouikila-Koussounda; Michel Bitemo; Brunelle Diassivy Matondo; Lee Aymar Ndounga Diakou; Leonardo K Basco; Francine Ntoumi
Journal:  Malar J       Date:  2015-10-29       Impact factor: 2.979

Review 3.  Malaria epidemiological research in the Republic of Congo.

Authors:  Felix Koukouikila-Koussounda; Francine Ntoumi
Journal:  Malar J       Date:  2016-12-23       Impact factor: 2.979

4.  Molecular surveillance of Plasmodium falciparum drug resistance in the Republic of Congo: four and nine years after the introduction of artemisinin-based combination therapy.

Authors:  Felix Koukouikila-Koussounda; Sankarganesh Jeyaraj; Christian N Nguetse; Charles Nchotebah Nkonganyi; Kossiwa Clarisse Kokou; Mandingha K Etoka-Beka; Francine Ntoumi; Thirumalaisamy P Velavan
Journal:  Malar J       Date:  2017-04-19       Impact factor: 2.979

5.  Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria in Dolisie, Republic of the Congo.

Authors:  Brice Pembet Singana; Prisca Nadine Casimiro; Brunelle Matondo Diassivi; Simon Charles Kobawila; Jean-Mermoz Youndouka; Leonardo K Basco; Pascal Ringwald; Sébastien Briolant; Mathieu Ndounga
Journal:  Malar J       Date:  2022-05-02       Impact factor: 3.469

6.  Artesunate-amodiaquine efficacy in Congolese children with acute uncomplicated falciparum malaria in Brazzaville.

Authors:  Mathieu Ndounga; Pembe Issamou Mayengue; Prisca Nadine Casimiro; Dieudonné Loumouamou; Leonardo K Basco; Francine Ntoumi; Philippe Brasseur
Journal:  Malar J       Date:  2013-02-05       Impact factor: 2.979

7.  Clinical efficacy of artemether-lumefantrine in congolese children with acute uncomplicated falciparum malaria in brazzaville.

Authors:  Mathieu Ndounga; Rachida Tahar; Prisca N Casimiro; Dieudonné Loumouamou; Leonardo K Basco
Journal:  Malar Res Treat       Date:  2012-12-17

8.  Malaria burden and anti-malarial drug efficacy in Owando, northern Congo.

Authors:  Brice P Singana; Hervé Bogreau; Brunelle D Matondo; Louis R Dossou-Yovo; Prisca N Casimiro; Rigobert Mbouka; Kim Yen Ha Nguyen; Bruno Pradines; Leonardo K Basco; Mathieu Ndounga
Journal:  Malar J       Date:  2016-01-08       Impact factor: 2.979

  8 in total

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