| Literature DB >> 18956338 |
Giuseppe Saccone1, Marco Salvemini, Attilio Pane, Lino C Polito.
Abstract
The Doublesex (DSX) transcription factor regulates somatic sexual differentiation in Drosophila melanogaster. Female and male isoforms (DSXF and DSXM) are produced due to sex-specific RNA splicing. Here we show that in the distantly related dipteran Ceratitis capitata, the DSXM male-specific isoform is conserved and able to induce masculinization of both somatic and germline tissues when ectopically expressed in XX Drosophila transgenic individuals.Entities:
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Year: 2008 PMID: 18956338 DOI: 10.1387/ijdb.082657gs
Source DB: PubMed Journal: Int J Dev Biol ISSN: 0214-6282 Impact factor: 2.203