Literature DB >> 18955087

Increased elevated plus maze open-arm time in mice during spontaneous morphine withdrawal.

Sam G Buckman1, Stephen R Hodgson, Rebecca S Hofford, Shoshana Eitan.   

Abstract

Rats undergoing both naloxone-precipitated and spontaneous opioid withdrawal exhibit anxiogenic behaviors in the elevated plus maze (EPM). Recently, we observed an unexpected result, namely mice exhibited increased EPM open-arm time during naloxone-precipitated morphine withdrawal. This was surprising since this behavioral outcome is usually associated with an anxiolytic profile. This study demonstrates that mice exhibit an increase in both EPM open-arm time and % open-arm entries also during spontaneous opioid withdrawal.

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Year:  2008        PMID： 18955087     DOI： 10.1016/j.bbr.2008.09.035

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN： 0166-4328            Impact factor:   3.332


  9 in total

1.  Social influences on morphine sensitization in adolescent females.

Authors:  Rebecca S Hofford; Kris W Roberts; Paul J Wellman; Shoshana Eitan
Journal:  Drug Alcohol Depend       Date:  2010-04-24       Impact factor: 4.492

2.  Increased opioid dependence in a mouse model of panic disorder.

Authors:  Xavier Gallego; Patricia Murtra; Teresa Zamalloa; Josep Maria Canals; Joseba Pineda; Alejandro Amador-Arjona; Rafael Maldonado; Mara Dierssen
Journal:  Front Behav Neurosci       Date:  2010-02-22       Impact factor: 3.558

3.  A history of chronic morphine exposure during adolescence increases despair-like behaviour and strain-dependently promotes sociability in abstinent adult mice.

Authors:  P E Lutz; D Reiss; A M Ouagazzal; B L Kieffer
Journal:  Behav Brain Res       Date:  2013-01-04       Impact factor: 3.332

4.  Chronic and intermittent morphine treatment differently regulates opioid and dopamine systems: a role in locomotor sensitization.

Authors:  Thierry Le Marec; Cynthia Marie-Claire; Florence Noble; Nicolas Marie
Journal:  Psychopharmacology (Berl)       Date:  2011-02-22       Impact factor: 4.530

5.  Socially induced morphine pseudosensitization in adolescent mice.

Authors:  Stephen R Hodgson; Rebecca S Hofford; Kris W Roberts; Paul J Wellman; Shoshana Eitan
Journal:  Behav Pharmacol       Date:  2010-03       Impact factor: 2.293

6.  Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains.

Authors:  G Ayranci; K Befort; L Lalanne; B L Kieffer; P-E Lutz
Journal:  Psychopharmacology (Berl)       Date:  2014-12-09       Impact factor: 4.530

7.  Extracellular signal-regulated kinase activation in the amygdala mediates elevated plus maze behavior during opioid withdrawal.

Authors:  Rebecca S Hofford; Stephen R Hodgson; Kris W Roberts; Camron D Bryant; Christopher J Evans; Shoshana Eitan
Journal:  Behav Pharmacol       Date:  2009-10       Impact factor: 2.293

8.  Study of the effects of controlled morphine administration for treatment of anxiety, depression and cognition impairment in morphine-addicted rats.

Authors:  Majid Motaghinejad; Sulail Fatima; Sanaz Banifazl; Mohammad Yasan Bangash; Morteza Karimian
Journal:  Adv Biomed Res       Date:  2016-11-28

Review 9.  Goofballing of Opioid and Methamphetamine: The Science Behind the Deadly Cocktail.

Authors:  Hanis Mohammad Hazani; Isa Naina Mohamed; Mustapha Muzaimi; Wael Mohamed; Mohamad Fairuz Yahaya; Seong Lin Teoh; Rashidi Mohamed Pakri Mohamed; Mohd Fadzli Mohamad Isa; Sundus Mansoor Abdulrahman; Ravi Ramadah; Mohammad Rahim Kamaluddin; Jaya Kumar
Journal:  Front Pharmacol       Date:  2022-04-07       Impact factor: 5.988
  9 in total

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