Literature DB >> 18953534

Virtual cardiotomy based on 3-D MRI for preoperative planning in congenital heart disease.

Thomas Sangild Sørensen1, Philipp Beerbaum, Jesper Mosegaard, Allan Rasmusson, Tobias Schaeffter, Conal Austin, Reza Razavi, Gerald Franz Greil.   

Abstract

BACKGROUND: Patient-specific preoperative planning in complex congenital heart disease may be greatly facilitated by virtual cardiotomy. Surgeons can perform an unlimited number of surgical incisions on a virtual 3-D reconstruction to evaluate the feasibility of different surgical strategies.
OBJECTIVE: To quantitatively evaluate the quality of the underlying imaging data and the accuracy of the corresponding segmentation, and to qualitatively evaluate the feasibility of virtual cardiotomy.
MATERIALS AND METHODS: A whole-heart MRI sequence was applied in 42 children with congenital heart disease (age 3 +/- 3 years, weight 13 +/- 9 kg, heart rate 96 +/- 21 bpm). Image quality was graded 1-4 (diagnostic image quality > or =2) by two independent blinded observers. In patients with diagnostic image quality the segmentation quality was also graded 1-4 (4 no discrepancies, 1 misleading error).
RESULTS: The average image quality score was 2.7 - sufficient for virtual reconstruction in 35 of 38 patients (92%) older than 1 month. Segmentation time was 59 +/- 10 min (average quality score 3.5). Virtual cardiotomy was performed in 19 patients.
CONCLUSION: Accurate virtual reconstructions of patient-specific cardiac anatomy can be produced in less than 1 h from 3-D MRI. The presented work thus introduces a new, clinically feasible noninvasive technique for improved preoperative planning in complex cases of congenital heart disease.

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Year:  2008        PMID: 18953534     DOI: 10.1007/s00247-008-1032-5

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  14 in total

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Authors:  T S Sørensen; S V Therkildsen; P Makowski; J L Knudsen; E M Pedersen
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2.  Operator-independent isotropic three-dimensional magnetic resonance imaging for morphology in congenital heart disease: a validation study.

Authors:  Thomas Sangild Sørensen; Hermann Körperich; Gerald F Greil; Joachim Eichhorn; Peter Barth; Hans Meyer; Erik Morre Pedersen; Philipp Beerbaum
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4.  Images in cardiovascular medicine. Virtual cardiotomy for preoperative planning.

Authors:  Thomas Sangild Sørensen; Jesper Mosegaard; Gerald Franz Greil; Stephan Miller; Achim Seeger; Ole Kromann Hansen; Ludger Sieverding
Journal:  Circulation       Date:  2007-03-06       Impact factor: 29.690

Review 5.  Computed tomography--an increasing source of radiation exposure.

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7.  Gadolinium-enhanced three-dimensional magnetic resonance angiography of pulmonary and systemic venous anomalies.

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8.  Three-dimensional morphological magnetic resonance imaging in infants and children with congenital heart disease.

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Journal:  Pediatr Radiol       Date:  2006-09-28

9.  Pediatric cardiac-gated CT angiography: assessment of radiation dose.

Authors:  Caroline L Hollingsworth; Terry T Yoshizumi; Donald P Frush; Frandics P Chan; Greta Toncheva; Giao Nguyen; Carolyn R Lowry; Lynne M Hurwitz
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4.  Visualization and simulated surgery of the left ventricle in the virtual pathological heart of the Virtual Physiological Human.

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5.  Use of magnetic resonance imaging combined with gene analysis for the diagnosis of fetal congenital heart disease.

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