Literature DB >> 18952648

Clinical and demographic evaluation of Behçet disease among different paediatric age groups.

G K Sungur1, D Hazirolan, I Yalvac, P A Ozer, D Yuksel, E T Vural, S Duman.   

Abstract

AIM: The aim of the study is to describe the demographic and clinical features of Behçet disease (BD) in paediatric patients.
METHODS: The study included 62 patients who presented to the Department of Ophthalmology at Ankara Education and Research Hospital, Ankara, Turkey and diagnosed as having BD. These patients were placed into three age groups based on the age at the time of BD presentation: group 1, birth to 10 years old; group 2, 11-15 years old; group 3, 16-20 years old. Among these three age groups, the objective was to identify the ocular and extraocular clinical findings and complications of BD, and to uncover the role of gender, if exists, in the aetiology of the disease.
RESULTS: The findings indicated that gender played no significant role in the aetiology of BD. In group 1, a family history of BD was more prevalent, and the most common ocular finding was bilateral anterior uveitis. The most frequent form of ocular involvement in groups 2 and 3 was bilateral panuveitis with retinal vasculitis and retinitis. The majority of disease complications were glaucoma, maculopathy and cataract formation.
CONCLUSION: Patient age appeared to define the type of ocular involvement in BD. While anterior uveitis was the most frequent ocular finding in BD patients younger than 10 years, panuveitis was the most frequent in patients older than 10 years. As a family history of BD was more frequent among patients younger than 10 years, family screening for BD is considered critical for early and accurate diagnosis of BD, as well as for the control of its complications.

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Year:  2008        PMID: 18952648     DOI: 10.1136/bjo.2007.137141

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  9 in total

1.  Late-onset Behçet's disease: demographic, clinical, and ocular features.

Authors:  Gulten Sungur; Dicle Hazirolan; Emre Hekimoglu; Remzi Kasim; Sunay Duman
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-05-07       Impact factor: 3.117

Review 2.  Clinical Manifestations and Management of Pediatric Behçet's Disease.

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Authors:  Ilknur Tugal-Tutkun
Journal:  J Ophthalmic Vis Res       Date:  2011-10

4.  A national cohort study on pediatric Behçet's disease: cross-sectional data from an Italian registry.

Authors:  Romina Gallizzi; Caterina Pidone; Luca Cantarini; Martina Finetti; Marco Cattalini; Giovanni Filocamo; Antonella Insalaco; Donato Rigante; Rita Consolini; Maria Cristina Maggio; Adele Civino; Silvana Martino; Alma Nunzia Olivieri; Giovanna Fabio; Serena Pastore; Angela Mauro; Diana Sutera; Giuseppe Trimarchi; Nicolino Ruperto; Marco Gattorno; Rolando Cimaz
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5.  Clinical manifestations and anti-TNF alpha therapy of juvenile Behçet's disease in Taiwan.

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Review 6.  Paediatric autoimmune and autoinflammatory conditions associated with uveitis.

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7.  [Ophthalmologic manifestations of Behçet's disease, about 33 cases].

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Authors:  Sira Nanthapisal; Nigel J Klein; Nicola Ambrose; Despina Eleftheriou; Paul A Brogan
Journal:  Clin Rheumatol       Date:  2016-02-01       Impact factor: 2.980

9.  Clinical profile and evolution of patients with juvenile-onset Behçet's syndrome over a 25-year period: insights from the AIDA network.

Authors:  Jurgen Sota; Donato Rigante; Giuseppe Lopalco; Giacomo Emmi; Stefano Gentileschi; Carla Gaggiano; Luisa Ciarcia; Virginia Berlengiero; Mariam Mourabi; Nicola Ricco; Sara Barneschi; Irene Mattioli; Gian Marco Tosi; Bruno Frediani; Maria Tarsia; Gerardo di Scala; Antonio Vitale; Florenzo Iannone; Claudia Fabiani; Luca Cantarini
Journal:  Intern Emerg Med       Date:  2021-04-09       Impact factor: 3.397

  9 in total

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