Literature DB >> 18952170

Current cellular immunological hurdles in pig-to-primate xenotransplantation.

Stéphanie Le Bas-Bernardet1, Gilles Blancho.   

Abstract

In this review, we summarize the work published over the last few years relative to cellular immunological hurdles encountered specifically in pig-to-primate xenotransplantation models. The works summarized here cover both the innate and adaptative cellular immune response as well as strategies to overcome them and consequently prevent xenograft rejection.

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Year:  2008        PMID: 18952170     DOI: 10.1016/j.trim.2008.10.006

Source DB:  PubMed          Journal:  Transpl Immunol        ISSN: 0966-3274            Impact factor:   1.708


  3 in total

1.  Relative efficiency of porcine and human cytotoxic T-lymphocyte antigen 4 immunoglobulin in inhibiting human CD4+ T-cell responses co-stimulated by porcine and human B7 molecules.

Authors:  Tadatsura Koshika; Carol Phelps; Jason Fang; Seung Eun Lee; Minoru Fujita; David Ayares; David K C Cooper; Hidetaka Hara
Journal:  Immunology       Date:  2011-12       Impact factor: 7.397

2.  Human cytokines activate JAK-STAT signaling pathway in porcine ocular tissue.

Authors:  Elizaveta Fasler-Kan; Natasha S Barteneva; Sylvia Ketterer; Kerstin Wunderlich; Anca Reschner; Asil Nurzhanova; Josef Flammer; Jörg Huwyler; Peter Meyer
Journal:  Xenotransplantation       Date:  2013-11-01       Impact factor: 3.907

3.  Neonatal Pig Sertoli Cells Survive Xenotransplantation by Creating an Immune Modulatory Environment Involving CD4 and CD8 Regulatory T Cells.

Authors:  Gurvinder Kaur; Kandis Wright; Payal Mital; Taylor Hibler; Jonathan M Miranda; Lea Ann Thompson; Katelyn Halley; Jannette M Dufour
Journal:  Cell Transplant       Date:  2020 Jan-Dec       Impact factor: 4.064

  3 in total

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