Literature DB >> 18950230

Oxidative burst inhibitory and cytotoxic indoloquinazoline and furoquinoline alkaloids from Oricia suaveolens.

Jean Duplex Wansi1, M Ahmed Mesaik, David Dako Chiozem, Krishna Prasad Devkota, Nicolas Gaboriaud-Kolar, Marie-Christine Lallemand, Jean Wandji, M Iqbal Choudhary, Norbert Sewald.   

Abstract

Two new β-indoloquinazoline alkaloids, orisuaveoline A (1) and orisuaveoline B (2), two new furoquinoline alkaloids, quinosuaveoline A (5) and quinosuaveoline B (6), and 12 known compounds were isolated from Oricia suaveolens. The structures of the new compounds were deduced by spectroscopic studies. The absolute configuration of nkolbisine (4) was also determined. Compounds 2, 3, 6-8, 10, and 14 were evaluated for oxidative burst inhibitory activity in a chemoluminescence assay and for cytotoxicity against A549 lung carcinoma cells.

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Year:  2008        PMID: 18950230     DOI: 10.1021/np800276f

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  Antiviral Potential of a Novel Compound CW-33 against Enterovirus A71 via Inhibition of Viral 2A Protease.

Authors:  Ching-Ying Wang; An-Cheng Huang; Mann-Jen Hour; Su-Hua Huang; Szu-Hao Kung; Chao-Hsien Chen; I-Chieh Chen; Yuan-Shiun Chang; Jin-Cherng Lien; Cheng-Wen Lin
Journal:  Viruses       Date:  2015-06-17       Impact factor: 5.048

2.  Hexafluoroisopropyl alcohol mediated synthesis of 2,3-dihydro-4H-pyrido[1,2-a]pyrimidin-4-ones.

Authors:  Mohammad A Alam; Zakeyah Alsharif; Hessa Alkhattabi; Derika Jones; Evan Delancey; Adam Gottsponer; Tianhong Yang
Journal:  Sci Rep       Date:  2016-11-02       Impact factor: 4.379

3.  Antimicrobial Furoquinoline Alkaloids from Vepris lecomteana (Pierre) Cheek & T. Heller (Rutaceae).

Authors:  Ariane Dolly Kenmogne Kouam; Achille Nouga Bissoue; Alain Tadjong Tcho; Emmanuel Ngeufa Happi; Alain François Kamdem Waffo; Norbert Sewald; Jean Duplex Wansi
Journal:  Molecules       Date:  2017-12-21       Impact factor: 4.411

4.  Exploring the Pharmacological Mechanism of the Herb Pair "HuangLian-GanJiang" against Colorectal Cancer Based on Network Pharmacology.

Authors:  Benjiao Gong; Yanlei Kao; Chenglin Zhang; Huishan Zhao; Fudong Sun; Zhaohua Gong
Journal:  Evid Based Complement Alternat Med       Date:  2019-11-29       Impact factor: 2.629

5.  Chemistry, taxonomy and ecology of the potentially chimpanzee-dispersed Vepris teva sp.nov. (Rutaceae) endangered in coastal thicket in the Congo Republic.

Authors:  Moses K Langat; Teva Kami; Martin Cheek
Journal:  PeerJ       Date:  2022-08-23       Impact factor: 3.061

6.  Antiviral Activity of a Novel Compound CW-33 against Japanese Encephalitis Virus through Inhibiting Intracellular Calcium Overload.

Authors:  Su-Hua Huang; Jin-Cherng Lien; Chao-Jung Chen; Yu-Ching Liu; Ching-Ying Wang; Chia-Fong Ping; Yu-Fong Lin; An-Cheng Huang; Cheng-Wen Lin
Journal:  Int J Mol Sci       Date:  2016-08-24       Impact factor: 5.923

  6 in total

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