Literature DB >> 18947312

Role of extracellular factors in axon regeneration in the CNS: implications for therapy.

Noreen M Gervasi1, Jessica Cf Kwok, James W Fawcett.   

Abstract

The glial scar that forms after an injury to the CNS contains molecules that are inhibitory to axon growth. Understanding of the mechanisms of inhibition has allowed the development of therapeutic strategies aimed at promoting axon regeneration. Promising results have been obtained in animal models, and some therapies are undergoing clinical trials. This offers great hope for achievement of functional recovery after CNS injury.

Mesh：

Year:  2008        PMID： 18947312     DOI： 10.2217/17460751.3.6.907

Source DB:  PubMed          Journal:  Regen Med        ISSN： 1746-0751            Impact factor:   3.806


  16 in total

Review 1.  The Neural Stem Cell Microenvironment: Focusing on Axon Guidance Molecules and Myelin-Associated Factors.

Authors:  Chao-Jin Xu; Jun-Ling Wang; Wei-Lin Jin
Journal:  J Mol Neurosci       Date:  2015-03-11       Impact factor: 3.444

2.  Diffuse traumatic axonal injury in the mouse induces atrophy, c-Jun activation, and axonal outgrowth in the axotomized neuronal population.

Authors:  John E Greer; Melissa J McGinn; John T Povlishock
Journal:  J Neurosci       Date:  2011-03-30       Impact factor: 6.167

3.  Regulatory mechanisms that mediate tenascin C-dependent inhibition of oligodendrocyte precursor differentiation.

Authors:  Tim Czopka; Alexander von Holst; Charles ffrench-Constant; Andreas Faissner
Journal:  J Neurosci       Date:  2010-09-15       Impact factor: 6.167

4.  Astrocytic YAP Promotes the Formation of Glia Scars and Neural Regeneration after Spinal Cord Injury.

Authors:  Changnan Xie; Xiya Shen; Xingxing Xu; Huitao Liu; Fayi Li; Sheng Lu; Ziran Gao; Jingjing Zhang; Qian Wu; Danlu Yang; Xiaomei Bao; Fan Zhang; Shiyang Wu; Zhaoting Lv; Minyu Zhu; Dingjun Xu; Peng Wang; Liying Cao; Wei Wang; Zengqiang Yuan; Ying Wang; Zhaoyun Li; Honglin Teng; Zhihui Huang
Journal:  J Neurosci       Date:  2020-02-17       Impact factor: 6.167

5.  Bridging the Divide between Neuroprosthetic Design, Tissue Engineering and Neurobiology.

Authors:  Jennie B Leach; Anil Kumar H Achyuta; Shashi K Murthy
Journal:  Front Neuroeng       Date:  2010-02-08

Review 6.  The glial scar in spinal cord injury and repair.

Authors:  Yi-Min Yuan; Cheng He
Journal:  Neurosci Bull       Date:  2013-07-16       Impact factor: 5.203

7.  Cell-type specific expression of constitutively-active Rheb promotes regeneration of bulbospinal respiratory axons following cervical SCI.

Authors:  Mark W Urban; Biswarup Ghosh; Laura R Strojny; Cole G Block; Sara M Blazejewski; Megan C Wright; George M Smith; Angelo C Lepore
Journal:  Exp Neurol       Date:  2018-02-14       Impact factor: 5.330

8.  TCTP Expression After Rat Spinal Cord Injury: Implications for Astrocyte Proliferation and Migration.

Authors:  Jianbing Ren; Xingxing Mao; Minghao Chen; Weidong Zhang; Yang Liu; Chengwei Duan; Haiyan Zhang; Chi Sun; Weijie Wu; Xinjian Zhu; Jianbing Ge; Weidong Tao; Youhua Wang; Hongjian Lu
Journal:  J Mol Neurosci       Date:  2015-08-13       Impact factor: 3.444

9.  Novel multi-modal strategies to promote brain and spinal cord injury recovery.

Authors:  Rajiv R Ratan; Mark Noble
Journal:  Stroke       Date:  2008-12-08       Impact factor: 7.914

Review 10.  Neuroinflammation in animal models of traumatic brain injury.

Authors:  Chong-Chi Chiu; Yi-En Liao; Ling-Yu Yang; Jing-Ya Wang; David Tweedie; Hanuma K Karnati; Nigel H Greig; Jia-Yi Wang
Journal:  J Neurosci Methods       Date:  2016-07-02       Impact factor: 2.390
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