| Literature DB >> 18942827 |
Savithri Ramurthy1, Sharadha Subramanian, Mina Aikawa, Payman Amiri, Abran Costales, Jeff Dove, Susan Fong, Johanna M Jansen, Barry Levine, Sylvia Ma, Christopher M McBride, Jonah Michaelian, Teresa Pick, Daniel J Poon, Sandhya Girish, Cynthia M Shafer, Darrin Stuart, Leonard Sung, Paul A Renhowe.
Abstract
A series of arylaminobenzimidazoles was designed and synthesized as Raf kinase inhibitors. Exploration of the structure-activity relationship resulted in compounds that are potent in vitro and show desirable in vivo properties.Entities:
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Year: 2008 PMID： 18942827 DOI： 10.1021/jm801050k
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446