Literature DB >> 18941610

Silent aortic dissection presenting as transient locked-in syndrome.

Wadih Nadour1, Brian Goldwasser, Robert W Biederman, Kevin Taffe.   

Abstract

Acute aortic dissection is a medical emergency. Without prompt recognition and treatment, the mortality rate is high. An atypical presentation makes timely diagnosis difficult, especially if the patient is experiencing no characteristic pain. Many patients with aortic dissection are reported to have presented with various neurologic manifestations, but none with only a presentation of transient locked-in syndrome.Herein, we report a case of completely painless aortic dissection in a woman who presented with a transient episode of anarthria, quadriplegia, and preserved consciousness. On physical examination, she had a 40-point difference in blood pressure between her left and right arms, and a loud diastolic murmur. The diagnosis of acute aortic dissection was reached via a combination of radiography, computed tomography, echocardiography, and a high index of clinical suspicion. The patient underwent emergency surgery and ultimately experienced a successful outcome.To our knowledge, this is the 1st report of aortic dissection that presented solely as locked-in syndrome. We suggest that silent aortic dissection be added to the differential diagnosis for transient locked-in syndrome.

Entities:  

Keywords:  Akinetic mutism/diagnosis/etiology; aneurysm, dissecting/diagnosis; aortic aneurysm/diagnosis; consciousness; quadriplegia/diagnosis/etiology/physiopathology; time factors

Mesh:

Year:  2008        PMID: 18941610      PMCID: PMC2565549     

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  8 in total

1.  Transient locked-in syndrome after uncal herniation.

Authors:  E F Wijdicks; G M Miller
Journal:  Neurology       Date:  1999-04-12       Impact factor: 9.910

2.  Dissecting aneurysm of the aorta: a review of 505 cases.

Authors:  A E HIRST; V J JOHNS; S W KIME
Journal:  Medicine (Baltimore)       Date:  1958-09       Impact factor: 1.889

3.  Transient locked-in syndrome resulting from stellate ganglion block in the treatment of patients with sudden hearing loss.

Authors:  M Tüz; F Erodlu; H Dodru; K Uygur; L Yavuz
Journal:  Acta Anaesthesiol Scand       Date:  2003-04       Impact factor: 2.105

4.  The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease.

Authors:  P G Hagan; C A Nienaber; E M Isselbacher; D Bruckman; D J Karavite; P L Russman; A Evangelista; R Fattori; T Suzuki; J K Oh; A G Moore; J F Malouf; L A Pape; C Gaca; U Sechtem; S Lenferink; H J Deutsch; H Diedrichs; J Marcos y Robles; A Llovet; D Gilon; S K Das; W F Armstrong; G M Deeb; K A Eagle
Journal:  JAMA       Date:  2000-02-16       Impact factor: 56.272

5.  Transient traumatic "locked-in" syndrome.

Authors:  B Chang; M A Morariu
Journal:  Eur Neurol       Date:  1979       Impact factor: 1.710

6.  Clinical and echocardiographic findings in patients with suspected acute aortic dissection.

Authors:  W F Armstrong; D S Bach; L M Carey; J Froehlich; M Lowell; E A Kazerooni
Journal:  Am Heart J       Date:  1998-12       Impact factor: 4.749

7.  Locked-in syndrome: a review of 139 cases.

Authors:  J R Patterson; M Grabois
Journal:  Stroke       Date:  1986 Jul-Aug       Impact factor: 7.914

8.  Association of painless acute aortic dissection with increased mortality.

Authors:  Seung Woo Park; Stuart Hutchison; Rajendra H Mehta; Eric M Isselbacher; Jeanna V Cooper; Jianming Fang; Arturo Evangelista; Alfredo Llovet; Christoph A Nienaber; Toru Suzuki; Linda A Pape; Kim A Eagle; Jae K Oh
Journal:  Mayo Clin Proc       Date:  2004-10       Impact factor: 7.616

  8 in total
  4 in total

1.  How to prevent inadvertent emergency anticoagulation in acute type A aortic dissection: when in doubt, don't.

Authors:  Silke Zschaler; Gerard Schmidt; Marian Kukucka; Georg Syrmas; Lisa Zaschke; Stephan Dominik Kurz
Journal:  Cardiovasc Diagn Ther       Date:  2018-12

2.  The prevalence and characteristics of patients with classic locked-in syndrome in Dutch nursing homes.

Authors:  R F Kohnen; J C M Lavrijsen; J H J Bor; R T C M Koopmans
Journal:  J Neurol       Date:  2013-01-11       Impact factor: 4.849

3.  Classic dissection of thoracic aorta complicated by ascending aortic intramural hematoma: promt diagnosis and successful endovascular repair.

Authors:  Gediminas Rackauskas; Mindaugas Mataciunas; Nerijus Misonis; Diana Zakarkaite; Marijus Gutauskas; Valdas Bilkis; Algirdas Edvardas Tamosiunas; Pranas Serpytis; Aleksandras Laucevicius
Journal:  Case Rep Med       Date:  2012-01-12

4.  Clinical analysis of aortic dissection with sudden coma and paraplegia as the main symptoms.

Authors:  Dongwei Zhang; Yinuo Lin; Yuehui Liu; Xinhong Zhang; Caixia Jiang
Journal:  J Int Med Res       Date:  2020-03       Impact factor: 1.671

  4 in total

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