Literature DB >> 18939372

Are we missing diagnostic opportunities in cases of carcinoid tumours of the appendix?

D Debnath1, J Rees, F Myint.   

Abstract

OBJECTIVE: Carcinoid tumour of appendix is an uncommon condition that can potentially give rise to a variation in management. We aimed to assess the occurrence and mode of presentation of carcinoid tumour of appendix, and any variation of its management.
METHODS: All appendicectomies that took place at North Middlesex University Hospital, London between 1995 and 2005 were considered for study.
RESULTS: A total of 1941 appendicectomies took place. Sixteen (0.82%) patients had carcinoid tumours. The mean age of patients with carcinoid tumour (41.8 years) was significantly higher than those with non-carcinoid pathology (27.7 years) (p = 0.001). The incidence of female patients was higher than the male amongst the carcinoid tumour group (female/male ratio 2.2). None of the carcinoid tumours were identified at operation. Eight patients as well as their general practitioners (53.3%) were unaware of the diagnosis. Multidisciplinary team involvement or specialty referral took place in three cases (20%). One patient (6.6%) required right hemicolectomy. Three patients (20%) were followed-up in inconsistent manner.
CONCLUSIONS: Carcinoid tumour of the appendix remains an incidental diagnosis. Patients with carcinoids were significantly older than non-carcinoid conditions. There was a trend of increased occurrence of carcinoids amongst the females. Re-operation rate was low. There was a wide variation in involving the multidisciplinary team, conveying the diagnosis to patients as well as their general practitioners, and follow-ups. This can be perceived as a missed opportunity of selective screening of synchronous and metachronous lesions, raises clinical governance issues and has medicolegal implications.

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Year:  2008        PMID: 18939372     DOI: 10.1016/s1479-666x(08)80049-2

Source DB:  PubMed          Journal:  Surgeon        ISSN: 1479-666X            Impact factor:   2.392


  4 in total

1.  Prevalence and clinicopathological characteristics of appendiceal carcinoids in Sharjah (United Arab Emirates).

Authors:  Khurshid Anwar; Munaf Desai; Noura Al-Bloushi; Farheen Alam; Farhan Sachal Cyprian
Journal:  World J Gastrointest Oncol       Date:  2014-07-15

2.  Appendiceal neuroendocrine tumors: Recent insights and clinical implications.

Authors:  John Griniatsos; Othon Michail
Journal:  World J Gastrointest Oncol       Date:  2010-04-15

3.  [Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor].

Authors:  T Gramann; L Matter; D Pfofe; R Flury; P Jaeger
Journal:  Urologe A       Date:  2009-11       Impact factor: 0.639

4.  Frequency, characteristics and outcomes of appendicular neuroendocrine tumors: A cross-sectional study from an academic tertiary care hospital.

Authors:  Abdelrahman Abdelaal; Walid El Ansari; Issam Al-Bozom; Mahwish Khawar; Fakhar Shahid; Ammar Aleter; Mohammed Rasoul Abunuwar; Ayman El-Menyar
Journal:  Ann Med Surg (Lond)       Date:  2017-07-19
  4 in total

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