Literature DB >> 189384

A trial of an alpha-adrenoreceptor blocking drug (indoramin) in exercise-induced bronchoconstriction.

J P Seale, S D Anderson, D A Lindsay.   

Abstract

In 10 patients with exercise-induced asthma oral indoramin, an alpha adrenoreceptor blocking drug, was ineffective in preventing the post-exercise fall in peak expiratory flow rate (PEFR). The values of PEFR at rest increased after administration of indoramin, providing indirect evidence for the existence of alpha receptors in the bronchial smooth muscle of asthmatic subjects.

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Year:  1976        PMID: 189384

Source DB:  PubMed          Journal:  Scand J Respir Dis        ISSN: 0036-5572


  3 in total

Review 1.  Exercise-induced asthma.

Authors:  P A Eggleston
Journal:  Clin Rev Allergy       Date:  1983-03

Review 2.  Indoramin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in hypertension and related vascular, cardiovascular and airway diseases.

Authors:  B Holmes; E M Sorkin
Journal:  Drugs       Date:  1986-06       Impact factor: 9.546

3.  The effects of indoramin on histamine and antigen-induced changes in respiration in guinea-pigs.

Authors:  C Hamer; D M Temple
Journal:  Agents Actions       Date:  1980-11
  3 in total

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