Primary invasive carcinoma of vagina with third degree uterovaginal prolapse: a case report and review of literature.

BACKGROUND: Primary vaginal carcinoma associated with third degree uterovaginal prolapse is very rare. CASE: We present a case report of a postmenopausal woman who presented with an invasive carcinoma of vagina associated with third degree uterovaginal prolapse treated by Mitra's operation. She was asymptomatic and had no recurrence during last 1 year of follow-up.
CONCLUSION: Vaginal ulcer associated with long standing genital prolapse need careful evaluation (including punch biopsy) for underlying carcinoma. Treatment due to the rarity of this entity was controversial previously and current review of literature suggests surgical treatment with or without radiotherapy as the optimum treatment for early stage and radiotherapy for advanced stage vaginal carcinoma associated with genital prolapse. Early diagnosis with adequate treatment can minimize the morbidity and mortality associated with vaginal carcinoma.