Literature DB >> 1893647

The use of benazepril in hypertensive patients age 55 and over.

W M Smith1, H J Gomez.   

Abstract

Benazepril, a newer angiotensin-converting enzyme inhibitor, has been evaluated for the treatment of mild to moderate hypertension in patients 55 years of age and older. The results of the clinical trials conducted to date indicate that benazepril provides effective antihypertensive therapy in this population, with efficacy comparable to that demonstrated in younger patients. Benazepril does not produce precipitous decreases in diastolic blood pressure following the initial dose, and is well tolerated by the elderly. It has a safety profile similar to that of placebo and generally better than that of hydrochlorothiazide.

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Year:  1991        PMID: 1893647     DOI: 10.1002/clc.4960141813

Source DB:  PubMed          Journal:  Clin Cardiol        ISSN: 0160-9289            Impact factor:   2.882


  3 in total

Review 1.  ACE inhibitors. Differential use in elderly patients with hypertension.

Authors:  Z H Israili; W D Hall
Journal:  Drugs Aging       Date:  1995-11       Impact factor: 3.923

Review 2.  Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension.

Authors:  Balraj S Heran; Michelle My Wong; Inderjit K Heran; James M Wright
Journal:  Cochrane Database Syst Rev       Date:  2008-10-08

3.  Pharmacokinetic interaction study between benazepril and amlodipine in healthy subjects.

Authors:  J X Sun; A Cipriano; K Chan; V A John
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

  3 in total

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