Literature DB >> 18936232

Hepcidin regulation of iron transport.

James F Collins1, Marianne Wessling-Resnick, Mitchell D Knutson.   

Abstract

The discovery of hepcidin as a key regulator of iron homeostasis has advanced our current knowledge of this field. Liver-derived hepcidin peptide is secreted in response to iron and inflammation and interacts with the iron export protein ferroportin. This review summarizes recent advances discussed at the Symposium. A particular focus is on molecular interactions between hepcidin and ferroportin, the regulation of hepcidin expression by iron and inflammation, and emerging methods to measure serum hepcidin in human populations.

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Year:  2008        PMID： 18936232      PMCID： PMC2764359          DOI： 10.3945/jn.108.096347

Source DB:  PubMed          Journal:  J Nutr        ISSN： 0022-3166            Impact factor:   4.798


  47 in total

1.  Adaptation of iron absorption in men consuming diets with high or low iron bioavailability.

Authors:  J R Hunt; Z K Roughead
Journal:  Am J Clin Nutr       Date:  2000-01       Impact factor: 7.045

2.  Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein.

Authors:  Elizabeta Nemeth; Erika V Valore; Mary Territo; Gary Schiller; Alan Lichtenstein; Tomas Ganz
Journal:  Blood       Date:  2002-11-14       Impact factor: 22.113

3.  Hepcidin, a urinary antimicrobial peptide synthesized in the liver.

Authors:  C H Park; E V Valore; A J Waring; T Ganz
Journal:  J Biol Chem       Date:  2000-12-11       Impact factor: 5.157

4.  Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation.

Authors:  Lijian Wang; Erin E Johnson; Hai Ning Shi; W Allan Walker; Marianne Wessling-Resnick; Bobby J Cherayil
Journal:  J Immunol       Date:  2008-08-15       Impact factor: 5.422

5.  Iron depletion limits intracellular bacterial growth in macrophages.

Authors:  Prasad N Paradkar; Ivana De Domenico; Nina Durchfort; Irene Zohn; Jerry Kaplan; Diane McVey Ward
Journal:  Blood       Date:  2008-03-27       Impact factor: 22.113

Review 6.  The ferroportin disease.

Authors:  Antonello Pietrangelo
Journal:  Blood Cells Mol Dis       Date:  2004 Jan-Feb       Impact factor: 3.039

7.  IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.

Authors:  Elizabeta Nemeth; Seth Rivera; Victoria Gabayan; Charlotte Keller; Sarah Taudorf; Bente K Pedersen; Tomas Ganz
Journal:  J Clin Invest       Date:  2004-05       Impact factor: 14.808

8.  Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis.

Authors:  George Papanikolaou; Mark E Samuels; Erwin H Ludwig; Marcia L E MacDonald; Patrick L Franchini; Marie-Pierre Dubé; Lisa Andres; Julie MacFarlane; Nikos Sakellaropoulos; Marianna Politou; Elizabeta Nemeth; Jay Thompson; Jenni K Risler; Catherine Zaborowska; Ryan Babakaiff; Christopher C Radomski; Terry D Pape; Owen Davidas; John Christakis; Pierre Brissot; Gillian Lockitch; Tomas Ganz; Michael R Hayden; Y Paul Goldberg
Journal:  Nat Genet       Date:  2003-11-30       Impact factor: 38.330

9.  Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene.

Authors:  G Montosi; A Donovan; A Totaro; C Garuti; E Pignatti; S Cassanelli; C C Trenor; P Gasparini; N C Andrews; A Pietrangelo
Journal:  J Clin Invest       Date:  2001-08       Impact factor: 14.808

10.  Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis.

Authors:  Antonella Roetto; George Papanikolaou; Marianna Politou; Federica Alberti; Domenico Girelli; John Christakis; Dimitris Loukopoulos; Clara Camaschella
Journal:  Nat Genet       Date:  2002-12-09       Impact factor: 38.330
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  37 in total

Review 1.  Diagnosis and management of iron deficiency anemia in patients with IBD.

Authors:  Jürgen Stein; Franz Hartmann; Axel U Dignass
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-10-05       Impact factor: 46.802

Review 2.  Iron, the retina and the lens: a focused review.

Authors:  Sixto García-Castiñeiras
Journal:  Exp Eye Res       Date:  2010-03-15       Impact factor: 3.467

3.  What regulates the iron regulator?

Authors:  Friedrich C Luft
Journal:  J Mol Med (Berl)       Date:  2009-05       Impact factor: 4.599

4.  DES-Mutation: System for Exploring Links of Mutations and Diseases.

Authors:  Vasiliki Kordopati; Adil Salhi; Rozaimi Razali; Aleksandar Radovanovic; Faroug Tifratene; Mahmut Uludag; Yu Li; Ameerah Bokhari; Ahdab AlSaieedi; Arwa Bin Raies; Christophe Van Neste; Magbubah Essack; Vladimir B Bajic
Journal:  Sci Rep       Date:  2018-09-06       Impact factor: 4.379

5.  Effect of iron supplementation during lactation on maternal iron status and oxidative stress: A randomized controlled trial.

Authors:  Josh M Jorgensen; Zhenyu Yang; Bo Lönnerdal; Caroline J Chantry; Kathryn G Dewey
Journal:  Matern Child Nutr       Date:  2016-11-29       Impact factor: 3.092

6.  Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2{alpha}) in intestinal epithelial cells.

Authors:  Liwei Xie; James F Collins
Journal:  Am J Physiol Cell Physiol       Date:  2011-02-23       Impact factor: 4.249

Review 7.  Pharmacology of iron transport.

Authors:  Shaina L Byrne; Divya Krishnamurthy; Marianne Wessling-Resnick
Journal:  Annu Rev Pharmacol Toxicol       Date:  2012-09-27       Impact factor: 13.820

8.  Maternal Perceived Stress during Pregnancy Increases Risk for Low Neonatal Iron at Delivery and Depletion of Storage Iron at One Year.

Authors:  Danielle N Rendina; Sharon E Blohowiak; Christopher L Coe; Pamela J Kling
Journal:  J Pediatr       Date:  2018-06-14       Impact factor: 4.406

9.  Non-mutagenic Suppression of Enterocyte Ferroportin 1 by Chemical Ribosomal Inactivation via p38 Mitogen-activated Protein Kinase (MAPK)-mediated Regulation: EVIDENCE FOR ENVIRONMENTAL HEMOCHROMATOSIS.

Authors:  Chang-Kyu Oh; Seong-Hwan Park; Juil Kim; Yuseok Moon
Journal:  J Biol Chem       Date:  2016-07-21       Impact factor: 5.157

10.  A chemical screen identifies small molecules that regulate hepcidin expression.

Authors:  Vera Gaun; Bonnie Patchen; Josephine Volovetz; Aileen W Zhen; Aleksandr Andreev; Michael P Pollastri; Paula G Fraenkel
Journal:  Blood Cells Mol Dis       Date:  2014-07-04       Impact factor: 3.039
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