Literature DB >> 18936052

REJECTOR: software for population history inference from genetic data via a rejection algorithm.

Matthew J Jobin1, Joanna L Mountain.   

Abstract

UNLABELLED: We introduce REJECTOR, software for parameter estimation and comparison of alternate models of population history from genetic data via a rejection algorithm. Through coalescent simulation, REJECTOR generates numerous gene genealogies, and hence simulated data, under a model of population history specified by the user. Summary statistics derived from such simulated data are compared with observed statistics, leading to acceptance or rejection of a given set of parameter values. We performed tests of the software using known parameter values in order to assess the inferential power provided by each summary statistic. The tests demonstrate the precision and accuracy of estimation made possible using this approach. AVAILABILITY: http://www.rejector.org

Mesh：

Year:  2008        PMID： 18936052      PMCID： PMC2639306          DOI： 10.1093/bioinformatics/btn540

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  8 in total

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  8 in total
  6 in total

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3.  Hunter-gatherer genomic diversity suggests a southern African origin for modern humans.

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5.  MTML-msBayes: approximate Bayesian comparative phylogeographic inference from multiple taxa and multiple loci with rate heterogeneity.

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6.  Distinguishing between selective sweeps from standing variation and from a de novo mutation.

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  6 in total

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