Literature DB >> 18932230

Insulin producing cells derived from embryonic stem cells: are we there yet?

Sudhanshu P Raikwar1, Nicholas Zavazava.   

Abstract

Derivation of insulin producing cells (IPCs) from embryonic stem (ES) cells provides a potentially innovative form of treatment for type 1 diabetes. Here, we discuss the current state of the art, unique challenges, and future directions on generating IPCs. (c) 2008 Wiley-Liss, Inc.

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Year:  2009        PMID： 18932230      PMCID： PMC2649936          DOI： 10.1002/jcp.21615

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  79 in total

1.  Bone marrow-derived stem cells initiate pancreatic regeneration.

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Review 2.  MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing.

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3.  Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.

Authors:  J Seufert; T J Kieffer; J F Habener
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-19       Impact factor: 11.205

4.  Blood glucose normalization upon transplantation of human embryonic pancreas into beta-cell-deficient SCID mice.

Authors:  M Castaing; B Péault; A Basmaciogullari; I Casal; P Czernichow; R Scharfmann
Journal:  Diabetologia       Date:  2001-11       Impact factor: 10.122

5.  A pancreatic islet-specific microRNA regulates insulin secretion.

Authors:  Matthew N Poy; Lena Eliasson; Jan Krutzfeldt; Satoru Kuwajima; Xiaosong Ma; Patrick E Macdonald; Sébastien Pfeffer; Thomas Tuschl; Nikolaus Rajewsky; Patrik Rorsman; Markus Stoffel
Journal:  Nature       Date:  2004-11-11       Impact factor: 49.962

6.  Nestin expression in pancreatic stellate cells and angiogenic endothelial cells.

Authors:  Jessy Lardon; Ilse Rooman; Luc Bouwens
Journal:  Histochem Cell Biol       Date:  2002-05-14       Impact factor: 4.304

7.  Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells.

Authors:  Yuichi Hori; Ingrid C Rulifson; Bernette C Tsai; Jeremy J Heit; John D Cahoy; Seung K Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-19       Impact factor: 11.205

8.  Nestin is expressed in vascular endothelial cells in the adult human pancreas.

Authors:  Tino Klein; Zhidong Ling; Harry Heimberg; Ole D Madsen; R Scott Heller; Palle Serup
Journal:  J Histochem Cytochem       Date:  2003-06       Impact factor: 2.479

9.  Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells.

Authors:  Przemyslaw Blyszczuk; Jaroslaw Czyz; Gabriela Kania; Martin Wagner; Ursula Roll; Luc St-Onge; Anna M Wobus
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-13       Impact factor: 11.205

10.  Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus.

Authors:  J Seufert; T J Kieffer; C A Leech; G G Holz; W Moritz; C Ricordi; J F Habener
Journal:  J Clin Endocrinol Metab       Date:  1999-02       Impact factor: 5.958
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  9 in total

Review 1.  Are Tanycytes the Missing Link Between Type 2 Diabetes and Alzheimer's Disease?

Authors:  Sudhanshu P Raikwar; Sachin M Bhagavan; Swathi Beladakere Ramaswamy; Ramasamy Thangavel; Iuliia Dubova; Govindhasamy Pushpavathi Selvakumar; Mohammad Ejaz Ahmed; Duraisamy Kempuraj; Smita Zaheer; Shankar Iyer; Asgar Zaheer
Journal:  Mol Neurobiol       Date:  2018-05-24       Impact factor: 5.590

2.  Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.

Authors:  Alice E Chen; Malgorzata Borowiak; Richard I Sherwood; Anastasie Kweudjeu; Douglas A Melton
Journal:  Development       Date:  2013-02-01       Impact factor: 6.868

3.  Differentiation of human labia minora dermis-derived fibroblasts into insulin-producing cells.

Authors:  Bona Kim; Byung Sun Yoon; Jai Hee Moon; Jonggun Kim; Eun Kyoung Jun; Jung Han Lee; Jun Sung Kim; Cheong Soon Baik; Aeree Kim; Kwang Youn Whang; Seungkwon You
Journal:  Exp Mol Med       Date:  2012-01-31       Impact factor: 8.718

4.  Cell replacement and regeneration therapy for diabetes.

Authors:  Hee-Sook Jun
Journal:  Korean Diabetes J       Date:  2010-04-30

5.  Genetic modification of primate amniotic fluid-derived stem cells produces pancreatic progenitor cells in vitro.

Authors:  Yu Zhou; David L Mack; J Koudy Williams; Sayed-Hadi Mirmalek-Sani; Emily Moorefield; So-Young Chun; Jun Wang; Diego Lorenzetti; Mark Furth; Anthony Atala; Shay Soker
Journal:  Cells Tissues Organs       Date:  2013-01-08       Impact factor: 2.481

Review 6.  Skin deep: from dermal fibroblasts to pancreatic beta cells.

Authors:  Gohar S Manzar; Eun-Mi Kim; Pavana Rotti; Nicholas Zavazava
Journal:  Immunol Res       Date:  2014-08       Impact factor: 2.829

7.  Improvement of the therapeutic capacity of insulin-producing cells trans-differentiated from human liver cells using engineered cell sheet.

Authors:  Yu Na Lee; Hye-Jin Yi; Eun Hye Seo; Jooyun Oh; Song Lee; Sarah Ferber; Teruo Okano; In Kyong Shim; Song Cheol Kim
Journal:  Stem Cell Res Ther       Date:  2021-01-06       Impact factor: 6.832

8.  PDX1-engineered embryonic stem cell-derived insulin producing cells regulate hyperglycemia in diabetic mice.

Authors:  Sudhanshu P Raikwar; Nicholas Zavazava
Journal:  Transplant Res       Date:  2012-10-18

9.  Establishment of Insulin-Producing Cells From Human Embryonic Stem Cells Underhypoxic Condition for Cell Based Therapy.

Authors:  Piyaporn Rattananinsruang; Chavaboon Dechsukhum; Wilairat Leeanansaksiri
Journal:  Front Cell Dev Biol       Date:  2018-05-15
  9 in total

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