Literature DB >> 18932085

Electrochemical and crystal structural analysis of alpha- and dehydro-alpha-lapachones.

H R Nasiri1, M Bolte, H Schwalbe.   

Abstract

Lapachones are pharmaceutically active compounds generating reactive oxygen species. The crystal structure and redox behaviour of the title lapachones, derivates of quinones, were determined by X-ray diffraction and cyclovoltametric measurements. The observed results were compared with beta-lapachone.

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Year:  2008        PMID: 18932085     DOI: 10.1080/14786410701654925

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  2 in total

1.  Ethyl (2S,4R)-4-(4-bromo-phen-yl)-2-hydr-oxy-5,10-dioxo-3,4,5,10-tetra-hydro-2H-benzo[g]chromene-2-carboxyl-ate.

Authors:  Wei Zhang; Yifeng Wang; Guangcun Zhang; Xiangsheng Xu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-01-16

2.  Understanding and predicting the potency of ROS-based enzyme inhibitors, exemplified by naphthoquinones and ubiquitin specific protease-2.

Authors:  Pushparathinam Gopinath; Atif Mahammed; Shimrit Ohayon; Zeev Gross; Ashraf Brik
Journal:  Chem Sci       Date:  2016-08-05       Impact factor: 9.825

  2 in total

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