Literature DB >> 18931770

Copper-catalyzed three-component coupling of arynes, terminal alkynes and activated alkenes.

Sivakolundu Bhuvaneswari1, Masilamani Jeganmohan, Chien-Hong Cheng.   

Abstract

The three-component coupling of benzynes with terminal alkynes and activated alkenes in the presence of CuI, PCy(3) and CsF in a 1:1 mixture of CH(3)CN and THF at 50 degrees C for 5 h gave 1-alkyl-2-alkynylbenzenes in good to moderate yields.

Entities:  

Year:  2008        PMID: 18931770     DOI: 10.1039/b809409h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Palladium-catalyzed annulation of arynes by o-halobenzamides: synthesis of phenanthridinones.

Authors:  Chun Lu; Anton V Dubrovskiy; Richard C Larock
Journal:  J Org Chem       Date:  2012-09-26       Impact factor: 4.354

2.  Cu(I)-Catalyzed 1,2-Alkynyl-propargylation and -benzylation of Benzyne Derivatives.

Authors:  Qile Wang; Thomas R Hoye
Journal:  Org Lett       Date:  2021-06-28       Impact factor: 6.072

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.