Literature DB >> 18931624

Project Accept (HPTN 043): a community-based intervention to reduce HIV incidence in populations at risk for HIV in sub-Saharan Africa and Thailand.

Gertrude Khumalo-Sakutukwa1, Stephen F Morin, Katherine Fritz, Edwin D Charlebois, Heidi van Rooyen, Alfred Chingono, Precious Modiba, Khalifa Mrumbi, Surasing Visrutaratna, Basant Singh, Michael Sweat, David D Celentano, Thomas J Coates.   

Abstract

BACKGROUND: Changing community norms to increase awareness of HIV status and reduce HIV-related stigma has the potential to reduce the incidence of HIV-1 infection in the developing world.
METHODS: We developed and implemented a multilevel intervention providing community-based HIV mobile voluntary counseling and testing, community mobilization, and posttest support services. Forty-eight communities in Tanzania, Zimbabwe, South Africa, and Thailand were randomized to receive the intervention or clinic-based standard voluntary counseling and testing (VCT), the comparison condition. We monitored utilization of community-based HIV mobile voluntary counseling and testing and clinic-based standard VCT by community of residence at 3 sites, which was used to assess differential uptake. We also developed quality assurance procedures to evaluate staff fidelity to the intervention.
FINDINGS: In the first year of the study, a 4-fold increase in testing was observed in the intervention versus comparison communities. We also found an overall 95% adherence to intervention components. Study outcomes, including prevalence of recent HIV infection and community-level HIV stigma, will be assessed after 3 years of intervention.
CONCLUSIONS: The provision of mobile services, combined with appropriate support activities, may have significant effects on utilization of voluntary counseling and testing. These findings also provide early support for community mobilization as a strategy for increasing testing rates.

Entities:  

Mesh:

Year:  2008        PMID: 18931624      PMCID: PMC2664736          DOI: 10.1097/QAI.0b013e31818a6cb5

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  23 in total

1.  Multiple levels of analysis and intervention in HIV prevention science: exemplars and directions for new research.

Authors:  C R Waldo; T J Coates
Journal:  AIDS       Date:  2000-09       Impact factor: 4.177

2.  Community-based approaches to HIV treatment in resource-poor settings.

Authors:  P Farmer; F Léandre; J S Mukherjee; M Claude; P Nevil; M C Smith-Fawzi; S P Koenig; A Castro; M C Becerra; J Sachs; A Attaran; J Y Kim
Journal:  Lancet       Date:  2001-08-04       Impact factor: 79.321

Review 3.  HIV transmission risk behaviors among HIV-positive individuals: stress and coping in the aftermath of 9/11.

Authors:  Carol S Dawson Rose; Barry Ress
Journal:  J Assoc Nurses AIDS Care       Date:  2002 Sep-Oct       Impact factor: 1.354

4.  Community-based voluntary counseling and testing services in rural communities of Chiang Mai Province, Northern Thailand.

Authors:  Surinda Kawichai; David D Celentano; Suwat Chariyalertsak; Surasing Visrutaratna; Onsri Short; Cholticha Ruangyuttikarn; Chonlisa Chariyalertsak; Becky Genberg; Chris Beyrer
Journal:  AIDS Behav       Date:  2007-05-15

5.  Social action theory for a public health psychology.

Authors:  C K Ewart
Journal:  Am Psychol       Date:  1991-09

6.  AIDS, sexuality, and sexual control.

Authors:  M C Quadland; W D Shattls
Journal:  J Homosex       Date:  1987

7.  Positive and negative life events after counselling and testing: the Voluntary HIV-1 Counselling and Testing Efficacy Study.

Authors:  O A Grinstead; S E Gregorich; K H Choi; T Coates
Journal:  AIDS       Date:  2001-05-25       Impact factor: 4.177

8.  Cost-effectiveness of voluntary HIV-1 counselling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania.

Authors:  M Sweat; S Gregorich; G Sangiwa; C Furlonge; D Balmer; C Kamenga; O Grinstead; T Coates
Journal:  Lancet       Date:  2000-07-08       Impact factor: 79.321

9.  The mislabeling of sexual impulsivity.

Authors:  R J Barth; B N Kinder
Journal:  J Sex Marital Ther       Date:  1987

10.  Impact and process evaluation of integrated community and clinic-based HIV-1 control: a cluster-randomised trial in eastern Zimbabwe.

Authors:  Simon Gregson; Saina Adamson; Spiwe Papaya; Jephias Mundondo; Constance A Nyamukapa; Peter R Mason; Geoffrey P Garnett; Stephen K Chandiwana; Geoff Foster; Roy M Anderson
Journal:  PLoS Med       Date:  2007-03-27       Impact factor: 11.069

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  86 in total

1.  Increasing access to HIV counseling and testing through mobile services in Kenya: strategies, utilization, and cost-effectiveness.

Authors:  Kristina L Grabbe; Nick Menzies; Miriam Taegtmeyer; Gideon Emukule; Patrick Angala; Irene Mwega; Geraldine Musango; Elizabeth Marum
Journal:  J Acquir Immune Defic Syndr       Date:  2010-07       Impact factor: 3.731

2.  HIV-related stigma, social norms, and HIV testing in Soweto and Vulindlela, South Africa: National Institutes of Mental Health Project Accept (HPTN 043).

Authors:  Sean D Young; Zdenek Hlavka; Precious Modiba; Glenda Gray; Heidi Van Rooyen; Linda Richter; Greg Szekeres; Thomas Coates
Journal:  J Acquir Immune Defic Syndr       Date:  2010-12-15       Impact factor: 3.731

3.  Linkage to HIV care from a mobile testing unit in South Africa by different CD4 count strata.

Authors:  Darshini Govindasamy; Nienke van Schaik; Katharina Kranzer; Robin Wood; Catherine Mathews; Linda-Gail Bekker
Journal:  J Acquir Immune Defic Syndr       Date:  2011-11-01       Impact factor: 3.731

4.  Venue-Based HIV-Testing: An Effective Screening Strategy for High-Risk Populations in Lima, Peru.

Authors:  Lao-Tzu Allan-Blitz; M Christina Herrera; Gino M Calvo; Silver K Vargas; Carlos F Caceres; Jeffrey D Klausner; Kelika A Konda
Journal:  AIDS Behav       Date:  2019-04

5.  HIV-related social intolerance and risky sexual behavior in a high HIV prevalence environment.

Authors:  Adeline Delavande; Mafalda Sampaio; Neeraj Sood
Journal:  Soc Sci Med       Date:  2014-04-13       Impact factor: 4.634

6.  Condoms "contain worms" and "cause HIV" in Tanzania: Negative Condom Beliefs Scale development and implications for HIV prevention.

Authors:  Aaron J Siegler; Jessie K Mbwambo; Frances A McCarty; Ralph J DiClemente
Journal:  Soc Sci Med       Date:  2012-07-27       Impact factor: 4.634

Review 7.  Combination implementation for HIV prevention: moving from clinical trial evidence to population-level effects.

Authors:  Larry W Chang; David Serwadda; Thomas C Quinn; Maria J Wawer; Ronald H Gray; Steven J Reynolds
Journal:  Lancet Infect Dis       Date:  2013-01       Impact factor: 25.071

8.  A Systematic Review of Interventions that Promote Frequent HIV Testing.

Authors:  Margaret M Paschen-Wolff; Arjee Restar; Anisha D Gandhi; Stephanie Serafino; Theodorus Sandfort
Journal:  AIDS Behav       Date:  2019-04

Review 9.  Behavioral and biomedical combination strategies for HIV prevention.

Authors:  Linda-Gail Bekker; Chris Beyrer; Thomas C Quinn
Journal:  Cold Spring Harb Perspect Med       Date:  2012-08-01       Impact factor: 6.915

10.  Comparison of two active case-finding strategies for community-based diagnosis of symptomatic smear-positive tuberculosis and control of infectious tuberculosis in Harare, Zimbabwe (DETECTB): a cluster-randomised trial.

Authors:  Elizabeth L Corbett; Tsitsi Bandason; Trinh Duong; Ethel Dauya; Beauty Makamure; Gavin J Churchyard; Brian G Williams; Shungu S Munyati; Anthony E Butterworth; Peter R Mason; Stanley Mungofa; Richard J Hayes
Journal:  Lancet       Date:  2010-10-09       Impact factor: 79.321

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