Literature DB >> 18930552

Nine-year incidence and risk factors for pterygium in the barbados eye studies.

Barbara Nemesure1, Suh-Yuh Wu, Anselm Hennis, M Cristina Leske.   

Abstract

PURPOSE: To present 9-year incidence data and associated risk factors for pterygium among black participants in the Barbados Eye Studies.
DESIGN: Population-based incidence study. PARTICIPANTS: A total of 1888 black participants, aged 40 to 84 years, who were free of pterygium at baseline and received an ophthalmologic study examination at the 9-year follow-up.
METHODS: Age and sex-specific 9-year incidence of pterygium is presented. Risk factors were initially identified using Mantel-Haenszel analyses, and significant factors (P<0.10) were subsequently included in multivariate logistic regression models. Odds ratios (OR) and 95% confidence intervals (CI) are provided. MAIN OUTCOME MEASURES: Development of pterygium, defined as the presence of a raised fleshy growth that crosses the limbus and encroaches onto the clear cornea.
RESULTS: The 9-year incidence of pterygium was 11.6% (95% CI, 10.1-13.1), with no clear pattern with increasing age and no statistically significant differences between genders. Multivariate logistic regression analyses indicated that having a lifetime outdoor job location was positively associated with the development of pterygium (OR = 1.51; 95% CI, 1.05-2.16), whereas darker skin color (OR = 0.67; 95% CI, 0.46-0.97) and use of any prescription lenses (OR = 0.58; 95% CI, 0.42-0.81) were found to be protective factors.
CONCLUSIONS: The incidence of pterygium was high in this population, for an average of 1.3% per year. Working outdoors increased the risk 1.5-fold, whereas having a darker skin complexion and using eyewear for either reading or distance substantially decreased the risk of developing pterygium. These data suggest that absorption of ultraviolet light plays a role in this condition and that preventive strategies are needed to decrease the burden of pterygium development in this and other populations. FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any materials discussed in this article.

Entities:  

Mesh:

Year:  2008        PMID: 18930552     DOI: 10.1016/j.ophtha.2008.08.003

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  30 in total

Review 1.  [Epidemiology of pterygium. A review].

Authors:  K Droutsas; W Sekundo
Journal:  Ophthalmologe       Date:  2010-06       Impact factor: 1.059

2.  Chronic inflammatory cells and damaged limbal cells in pterygium.

Authors:  P Anguria; T Carmichael; S Ntuli; J Kitinya
Journal:  Afr Health Sci       Date:  2013-09       Impact factor: 0.927

3.  Prevalence and racial differences in pterygium: a cross-sectional study in Han and Uygur adults in Xinjiang, China.

Authors:  Ting Chen; Lin Ding; Guangliang Shan; Limujiang Ke; Jin Ma; Yong Zhong
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-01-27       Impact factor: 4.799

Review 4.  The role of heredity in pterygium development.

Authors:  Peter Anguria; James Kitinya; Sam Ntuli; Trevor Carmichael
Journal:  Int J Ophthalmol       Date:  2014-06-18       Impact factor: 1.779

5.  A comparison between fibrin sealant and sutures for attaching conjunctival autograft after pterygium excision.

Authors:  Nitin Vichare; Tarun Choudhary; Priyanka Arora
Journal:  Med J Armed Forces India       Date:  2012-12-29

6.  Risk Factors for Pterygium in Ilam Province, Iran.

Authors:  Parviz Malekifar; Hamed Esfandiari; Nazanin Behnaz; Fatemeh Javadi; Sima Azish; Mohammad Ali Javadi; Masumeh Kalantarion
Journal:  J Ophthalmic Vis Res       Date:  2017 Jul-Sep

Review 7.  Pterygium: an update on pathophysiology, clinical features, and management.

Authors:  Toktam Shahraki; Amir Arabi; Sepehr Feizi
Journal:  Ther Adv Ophthalmol       Date:  2021-05-31

8.  Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation.

Authors:  Mohamed A E Soliman Mahdy; Jagdish Bhatia
Journal:  Oman J Ophthalmol       Date:  2009-01

9.  Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Pterygium by MeRIP Sequencing.

Authors:  Yaping Jiang; Xin Zhang; Xiaoyan Zhang; Kun Zhao; Jing Zhang; Chuanxi Yang; Yihui Chen
Journal:  Front Cell Dev Biol       Date:  2021-06-25

10.  Oral doxycycline reduces pterygium lesions; results from a double blind, randomized, placebo controlled clinical trial.

Authors:  Oscar Rúa; Ignacio M Larráyoz; María T Barajas; Sara Velilla; Alfredo Martínez
Journal:  PLoS One       Date:  2012-12-19       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.